Research Paper Volume 12, Issue 22 pp 22626—22655

Colon cancer-specific diagnostic and prognostic biomarkers based on genome-wide abnormal DNA methylation

Figure 7. Kaplan-Meier and ROC analysis results based on stage, examined lymph node count and lymphatic invasion. (A) Grouping of COAD patients according to stage: early (stage I and II [N = 153, 53.31%]) and advanced (stage III and IV [N = 124, 43.21%]). (B) Grouping of COAD patients according to examined lymph node count: < 12 (N = 42, 14.63%) and ≥ 12 (N = 226, 78.75%). (C) Grouping of COAD patients according to lymphatic invasion: lymphatic invasion (N = 76, 26.48%) and no lymphatic invasion (N = 175, 60.98%).