Research Paper Volume 12, Issue 22 pp 23082—23095

Deubiquitinase USP7 regulates Drosophila aging through ubiquitination and autophagy

Figure 3. Effect of dusp7 knockdown on the intestinal function of Drosophila. (A) Effect on the intestinal integrity of Drosophila after systemic knockdown of the ubiquitin-specific protease dUSP7(*** p<0.001). (B) Effect on intestinal integrity of Drosophila after gut-specific knockdown of the ubiquitin-specific protease dUSP7 (* p<0.05; ** p<0.01; *** p<0.001). (>: hybridization).