Research Paper Volume 12, Issue 21 pp 22291—22312

LncRNA PVT1 accelerates malignant phenotypes of bladder cancer cells by modulating miR-194-5p/BCLAF1 axis as a ceRNA

Figure 3. PVT1 affected the BC cell migration and apoptosis. The relative cell migration was restrained after transfection of siRNA in the T24 and UM-UC-3 (A, B) cell lines. The relative cell migration was facilitated after transfection of pcDNA3.1-PVT1 in the SV-HUC-1 cell lines (C). Apoptotic cells were measured after transfection of siRNA in the T24 (D) and UM-UC-3 (E) cell lines, of pcDNA3.1 in the SV-HUC-1 cell line (F) by flow cytometry analysis. (*P < 0.05, **P < 0.01).