Research Paper Advance Articles pp 23525—23547

Mutation in histone deacetylase HDA-3 leads to shortened locomotor healthspan in Caenorhabditis elegans

Figure 4. HDA-3 mutation leads to shortened lifespan. (A) Lifespan of WT (N = 80), OF1355 hda-3(ix261) (N=60), OF1356 hda-3(ix261) (N=66), and hda-3(ok1991) worms (N = 64). (B) Body length of WT, OF1355 hda-3(ix261), and OF1356 hda-3(ix261) worms. N = 10-17 worms per strain. (C) Development time of WT, OF1355 hda-3(ix261), and OF1356 hda-3(ix261) worms. N = 8-10 worms per strain. (D) Brood size of WT, OF1355 hda-3(ix261), and OF1356 hda-3(ix261) worms N = 5-6 worms per strain. *p < 0.05.