Research Paper Volume 13, Issue 14 pp 18870—18878

Atorvastatin attenuates intermittent hypoxia-induced myocardial oxidative stress in a mouse obstructive sleep apnea model

Mean body weight by group at indicated time points. Two-way ANOVA for repeated measures was used to examine interaction effects between week and CIH; the results showed that this interaction was not statistically significant [F = 0.494, p > 0.05]. Body weights tended to be lower in the CIH group during the last 3 weeks than in the normoxia group, but this difference did not reach statistical significance (CIH + vehicle vs. normoxia + vehicle: 23.58 ± 2.35 vs. 26.01 ± 2.58 at week 10, 24.36 ± 2.18 vs. 26.35 ± 2.18 at week 11, and 24.32 ± 2.13 vs. 27.84 ± 2.32 at week 12, p > 0.05).

Figure 1. Mean body weight by group at indicated time points. Two-way ANOVA for repeated measures was used to examine interaction effects between week and CIH; the results showed that this interaction was not statistically significant [F = 0.494, p > 0.05]. Body weights tended to be lower in the CIH group during the last 3 weeks than in the normoxia group, but this difference did not reach statistical significance (CIH + vehicle vs. normoxia + vehicle: 23.58 ± 2.35 vs. 26.01 ± 2.58 at week 10, 24.36 ± 2.18 vs. 26.35 ± 2.18 at week 11, and 24.32 ± 2.13 vs. 27.84 ± 2.32 at week 12, p > 0.05).