Research Paper Volume 13, Issue 14 pp 17970

Prognoses and genomic analyses of proteasome 26S subunit, ATPase (PSMC) family genes in clinical breast cancer

Coexpression of proteasome 26S subunit, ATPase (PSMC) genes and signal transduction pathways in breast cancer tissues. (A) Venn diagram of PSMC family coexpression networks in METABRIC breast cancer databases. PSMC genes were analyzed using METABRIC databases, and the intersection of coexpressed genes was plotted. (B) To explore potential networks regulated by PSMC family genes, we exported coexpressed genes and further uploaded them to the MetaCore platform for a pathway analysis. (C) The MetaCore pathway analysis of "biological processes" indicated that “Cytoskeleton remodeling

Figure 7. Coexpression of proteasome 26S subunit, ATPase (PSMC) genes and signal transduction pathways in breast cancer tissues. (A) Venn diagram of PSMC family coexpression networks in METABRIC breast cancer databases. PSMC genes were analyzed using METABRIC databases, and the intersection of coexpressed genes was plotted. (B) To explore potential networks regulated by PSMC family genes, we exported coexpressed genes and further uploaded them to the MetaCore platform for a pathway analysis. (C) The MetaCore pathway analysis of "biological processes" indicated that “Cytoskeleton remodeling_Regulation of actin cytoskeleton organization by the kinase effectors of Rho GTPases"-related pathways were correlated with breast cancer development.