Research Paper Volume 13, Issue 16 pp 20218—20228

ERCC6L promotes cell growth and metastasis in gastric cancer through activating NF-κB signaling

The effects of ERCC6L overexpression or knockdown on GC cells growth, migration and invasion in vitro. Following ERCC6L overexpression or knockdown treatment, CCK-8 assay (A), colony formation assay (B) and EdU assay (C) were used to evaluate the effects of ERCC6L expression on the proliferation ability of GC cells. The wound-healing assay (D), transwell migration and invasion assays (E) were employed to assess the effects of ERCC6L overexpression or knockdown on the migration and invasion ability of GC cells. *P

Figure 3. The effects of ERCC6L overexpression or knockdown on GC cells growth, migration and invasion in vitro. Following ERCC6L overexpression or knockdown treatment, CCK-8 assay (A), colony formation assay (B) and EdU assay (C) were used to evaluate the effects of ERCC6L expression on the proliferation ability of GC cells. The wound-healing assay (D), transwell migration and invasion assays (E) were employed to assess the effects of ERCC6L overexpression or knockdown on the migration and invasion ability of GC cells. *P < 0.05.