COVID-19 Research Paper Volume 13, Issue 17 pp 20860—20885

Circulating acetylated polyamines correlate with Covid-19 severity in cancer patients

Acetylated polyamine derivatives and associated metabolites in cancer patients with different levels of Covid-19 severity. Acetylated polyamine derivatives were identified by targeted metabolomics data (A). S-adenosylhomocysteine and S-adenosylmethionine are shown (B). All data represent the normalized areas of mass spectrometric peaks and were analyzed by non-parametric unpaired Wilcoxon test (Mann–Whitney) for each two-group comparison. The black bar of the figure indicates the p-value.

Figure 3. Acetylated polyamine derivatives and associated metabolites in cancer patients with different levels of Covid-19 severity. Acetylated polyamine derivatives were identified by targeted metabolomics data (A). S-adenosylhomocysteine and S-adenosylmethionine are shown (B). All data represent the normalized areas of mass spectrometric peaks and were analyzed by non-parametric unpaired Wilcoxon test (Mann–Whitney) for each two-group comparison. The black bar of the figure indicates the p-value.