Research Paper Volume 13, Issue 21 pp 24271—24289

Immunological and clinical immunotherapy implications of NLRP3 mutations in melanoma

The mutational patterns of NLR family members and genome maintenance genes. (A) TMB stratified by synonymous and non-synonymous mutations for each patient. (B) Waterfall plot for NLR family members and genome maintenance genes. (C) Association of NLRP3 mutations with BRCA1/2, TP53, POLE, and MMR genes mutations.

Figure 1. The mutational patterns of NLR family members and genome maintenance genes. (A) TMB stratified by synonymous and non-synonymous mutations for each patient. (B) Waterfall plot for NLR family members and genome maintenance genes. (C) Association of NLRP3 mutations with BRCA1/2, TP53, POLE, and MMR genes mutations.