Research Paper Volume 13, Issue 21 pp 24271—24289

Immunological and clinical immunotherapy implications of NLRP3 mutations in melanoma

Association of NLRP3 mutations with TMB, NB, and genomic features. (A, B) NLRP3 mutations versus TMB with univariate analysis and multivariate regression model. (C, D) NLRP3 mutations versus NB with univariate analysis and multivariate regression model. NLRP3 mutations association with (E) tumor heterogeneity, (F) purity, and (G) ploidy.

Figure 2. Association of NLRP3 mutations with TMB, NB, and genomic features. (A, B) NLRP3 mutations versus TMB with univariate analysis and multivariate regression model. (C, D) NLRP3 mutations versus NB with univariate analysis and multivariate regression model. NLRP3 mutations association with (E) tumor heterogeneity, (F) purity, and (G) ploidy.