Research Paper Volume 13, Issue 23 pp 25518—25549

Identification of a novel immune signature for optimizing prognosis and treatment prediction in colorectal cancer

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Figure 1. Exploration of the predictive power and clinical characteristics of seven IRGs signature in the training cohort. (A) Distribution of risk score, survival status, and expression of seven IRGs of CRCs. (B) Kaplan-Meier survival curve of the high- and low- risk subgroups. (C) ROC curve analysis of IRGs. (D) Univariate Cox analysis of prognostic factors and OS of CRCs. (E) Violin plot illustrated the correlation between risk score and tumor site as well as tumor stage. (F) Alluvial diagram for the two subtypes versus different immune subtypes and CMS. (G) Violin plot illustrated the correlation between risk score and immune subtypes, and (H) CMS. AUC, area under the curve; OS, overall survival; CRC, colorectal cancer; IRGs, immune-related genes; ROC, receiver operating characteristic; CMS, consensus molecular subtypes.