Research Paper Volume 14, Issue 11 pp 4914—4926

CircSOX9 acts as a molecular sponge of miR-485-3p to promote the progression of nasopharyngeal carcinoma

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Figure 1. CircSOX9 is increased in NPC cells and tissues. (A) Bioinformatic analysis the circSOX9 expression in the GEO database (GSE143797). (B) The tumor tissues and para-tumor tissues of 60 patients were collected, and the expression difference of circSOX9 was detected by qRT-PCR. (C) Count the expression of NPC and para-tumor in each patient, T/P: tumor vs para-tumor. (D) qRT-PCR was used to detect the expression of circSOX9 in NPC cell lines NP69, HK-1, HONE1, CNE2, SUNE1, and C666-1. (E) The relationship between the expression of circSOX9 in tumor tissues and overall survival. (F) The relationship between the expression of circSOX9 in tumor tissues and its recurrence.*P < 0.05, **P < 0.01, ***P < 0.001.