Research Paper Volume 15, Issue 18 pp 9438—9452

Astragalus polysaccharide inhibits the development of urothelial carcinoma by activating AMPK signaling to induce BENC1-xCT complex formation

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Figure 1. APS inhibits the proliferation and migration of RT4 and T24 cells. CCK-8 assays revealed that APS significantly inhibited the viability of RT4 (A) and T24 (B) cells. The transwell results revealed that 15 and 10 μM APS significantly inhibited the migration of RT4 (C) and T24 (D) cells (Bar represents 10 μm, 20 × magnification). Scratch assays confirmed that 15 and 10 μM APS significantly reduced the migration of RT4 (E) and T24 (F) cells (Bar represents 50 μm, 4 × magnification). *p < 0.05, **p < 0.01 vs. Con.