Research Paper Advance Articles

Evaluating the nonlinear effects of sleep duration on biological aging across phenotypic, genomic, and epigenomic data

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Figure 4. Mendelian randomization estimates for PhenoAge acceleration (PhenoAgeAccel), BioAge acceleration (BioAgeAccel), and leukocyte telomere length in overall population and strata of population defined by residual sleep duration. Grey circles denote overall estimates, and blue circles denote stratum estimates. Error bars denote 95% confidence intervals. Models adjusted for: age at baseline, sex, the top five genetic principal components, and genotyping array.