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• Research PaperVolume 12, Issue 7pp 6151-6171

  Systemic administration of the di-apocarotenoid norbixin (BIO201) is neuroprotective, preserves photoreceptor function and inhibits A2E and lipofuscin accumulation in animal models of age-related macular degeneration and Stargardt disease

  Relevance score: 0.00

  Valérie Fontaine, Elodie Monteiro, Mylène Fournié, Elena Brazhnikova, Thinhinane Boumedine, Cécile Vidal, Christine Balducci, Louis Guibout, Mathilde Latil, Pierre J. Dilda, Stanislas Veillet, José-Alain Sahel, René Lafont, Serge Camelo

  Keywords: norbixin, retinal function, A2E, AMD, Stargardt disease

  Published in Aging on April 7, 2020

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• Priority Research PaperVolume 12, Issue 24pp 24504-24521

  Neuroprotective effects and mechanisms of action of nicotinamide mononucleotide (NMN) in a photoreceptor degenerative model of retinal detachment

  Relevance score: 0.00

  Xiaohong Chen, João A. Amorim, Giannis A. Moustafa, Jong-Jer Lee, Zhen Yu, Kenji Ishihara, Yasuhiro Iesato, Paulo Barbisan, Takashi Ueta, Konstantina A. Togka, Lin Lu, David A. Sinclair, Demetrios G. Vavvas

  Keywords: nicotinamide mononucleotide, photoreceptor degeneration, NAD⁺, SIRT1, neuroprotection

  Published in Aging on December 29, 2020

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• Research PaperVolume 13, Issue 8pp 10866-10890

  Pharmacologic activation of autophagy without direct mTOR inhibition as a therapeutic strategy for treating dry macular degeneration

  Relevance score: 0.00

  Qitao Zhang, Feriel Presswalla, Robin R. Ali, David N. Zacks, Debra A. Thompson, Jason ML. Miller

  Keywords: age-related macular degeneration (AMD), drusen, lipofuscin, retinal pigment epithelium (RPE), autophagy

  Published in Aging on April 19, 2021

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• Research PaperVolume 2, Issue 1pp 28-42

  Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: Relevance to age-related macular degeneration

  Relevance score: 0.00

  Shozo Sonoda, Parameswaran G. Sreekumar, Satoru Kase, Christine Spee, Stephen J Ryan, Ram Kannan, David R Hinton

  Keywords: retinal pigment epithelial cell, cell polarity, VEGF-A, PEDF, BMP-4, age-related macular degeneration

  Published in Aging on December 27, 2009

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• Research ArticleVolume 8, Issue 9pp 1952-1978

  PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration

  Relevance score: 0.00

  Mayur Choudhary, Jin-dong Ding, Xiaoping Qi, Michael E. Boulton, Pei-Li Yao, Jeffrey M. Peters, Goldis Malek

  Keywords: age-related macular degeneration, PPARβ/δ, nuclear receptors, inflammation, angiogenesis, choroidal neovascularization

  Published in Aging on September 8, 2016

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• Research PaperVolume 3, Issue 1pp 44-54

  Alterations of retinal pigment epithelium cause AMD-like retinopathy in senescence-accelerated OXYS rats

  Relevance score: 0.00

  Anton M. Markovets, Valeriya B. Saprunova, Anna A. Zhdankina, Anzhella Zh. Fursova, Lora E. Bakeeva, Natalia G. Kolosova

  Keywords: age-related macular degeneration, OXYS rats, molecular mechanism of pathogenesis, vascular endothelial growth factor, pigment epithelium-derived factor

  Published in Aging on December 12, 2010

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• Research PaperVolume 2, Issue 12pp 981-989

  CD36 plays an important role in the clearance of oxLDL and associated age-dependent sub-retinal deposits

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  Emilie Picard, Marianne Houssier, Kim Bujold, Przemyslaw Sapieha, William Lubell, Allison Dorfman, Julie Racine, Pierre Hardy, Maria Febbraio, Pierre Lachapelle, Huy Ong, Florian Sennlaub, Sylvain Chemtob

  Keywords: CD36, oxidized lipids, Bruch's membrane, age-related macular degeneration

  Published in Aging on November 9, 2010

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• Research PaperVolume 11, Issue 20pp 8969-8981

  Expression and significance of miR - 20b in retinal photoreceptor cells exposed to PCB₁₂₅₄

  Relevance score: 0.00

  Xin Zhang, Qingyu Zhang, Yue Jiang, Shuchun Zhang, Qin Hong, Xirong Guo, Xia Chi, Meiling Tong

  Keywords: PCB ₁₂₅₄, miR-20b, MAPK signaling pathway

  Published in Aging on October 16, 2019

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• Research PaperVolume 9, Issue 10pp 2052-2068

  PKCζ-dependent upregulation of p27kip1 contributes to oxidative stress induced retinal pigment epithelial cell multinucleation

  Relevance score: 0.00

  Dinusha Rajapakse, Mei Chen, Tim M. Curtis, Heping Xu

  Keywords: aging, multinucleation, retinal pigment epithelium, protein kinase C, p27kip1

  Published in Aging on October 9, 2017

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• Research PaperVolume 15, Issue 2pp 396-420

  Light modulates Drosophila lifespan via perceptual systems independent of circadian rhythms

  Relevance score: 0.00

  Jacob C. Johnson, Allyson S. Munneke, Haley M. Richardson, Christi M. Gendron, Scott D. Pletcher

  Keywords: sensory perception, aging, circadian clock, model systems, shift work

  Published in Aging on January 6, 2023

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• Research PaperVolume 10, Issue 6pp 1380-1389

  The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells – implication in subretinal immune privilege in the aging eye

  Relevance score: 0.00

  Chang Luo, Jiawu Zhao, Mei Chen, Heping Xu

  Keywords: macrophages, retinal pigment epithelial cells, complement, aging, subretinal immune privilege

  Published in Aging on June 13, 2018

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