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• Research PaperVolume 12, Issue 23pp 23619-23646

  Pathomechanism characterization and potential therapeutics identification for SCA3 targeting neuroinflammation

  Relevance score: 0.00

  Ya-Jen Chiu, Shu-An Lin, Wan-Ling Chen, Te-Hsien Lin, Chih-Hsin Lin, Ching-Fa Yao, Wenwei Lin, Yih-Ru Wu, Kuo-Hsuan Chang, Guey-Jen Lee-Chen, Chiung-Mei Chen

  Keywords: spinocerebellar ataxia 3/ATXN3, IL-1β, IkBα/P65, JNK/JUN, P38/STAT1, therapeutics

  Published in Aging on November 10, 2020

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• Research PaperVolume 12, Issue 6pp 4742-4756

  Genome-wide association study identifies genetic factors that modify age at onset in Machado-Joseph disease

  Relevance score: 0.00

  Fulya Akçimen, Sandra Martins, Calwing Liao, Cynthia V. Bourassa, Hélène Catoire, Garth A. Nicholson, Olaf Riess, Mafalda Raposo, Marcondes C. França, João Vasconcelos, Manuela Lima, Iscia Lopes-Cendes, Maria Luiza Saraiva-Pereira, Laura B. Jardim, Jorge Sequeiros, Patrick A. Dion, Guy A. Rouleau

  Keywords: Machado-Joseph disease, GWAS, age at onset, ATXN3, modifier

  Published in Aging on March 23, 2020

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