Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Individualizing treatment targets for elderly patients with type 2 diabetes: factors influencing clinical decision making in the 24-week, randomized INTERVAL study

W. David Strain, Abhijit S. Agarwal, Päivi M. Paldánius,

https://doi.org/10.18632/aging.101188 pp 769—777

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The stress polarity pathway: AMPK 'GIV'-es protection against metabolic insults

Pradipta Ghosh,

https://doi.org/10.18632/aging.101179 pp 303—314

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Rapamycin treatment benefits glucose metabolism in mouse models of type 2 diabetes

Peter C. Reifsnyder, Kevin Flurkey, Austen Te, David E. Harrison,

https://doi.org/10.18632/aging.101117 pp 3120—3130

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Biological and biophysics aspects of metformin-induced effects: cortex mitochondrial dysfunction and promotion of toxic amyloid pre-fibrillar aggregates

Pasquale Picone, Silvia Vilasi, Fabio Librizzi, Marco Contardi, Domenico Nuzzo, Luca Caruana, Sara Baldassano, Antonella Amato, Flavia Mulè, Pier Luigi San Biagio, Daniela Giacomazza, Marta Di Carlo,

https://doi.org/10.18632/aging.101004 pp 1718—1734

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Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice

Felipe C. G. C. Reis, Jéssica L. O. L. Branquinho, Bruna B. B. Brandão, Beatriz A. A. Guerra, Ismael D. D. Silva, Andrea Frontini, Thomas Thomou, Loris Sartini, Saverio Cinti, C. Ronald Ronald Kahn, William T. T. Festuccia, Alicia J. J. Kowaltowski, Marcelo A. A. Mori,

https://doi.org/10.18632/aging.100970 pp 1201—1215

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Metabolic consequences of long-term rapamycin exposure on common marmoset monkeys (Callithrix jacchus)

Corinna Ross, Adam Salmon, Randy Strong, Elizabeth Fernandez, Marty Javors, Arlan Richardson, Suzette Tardif,

https://doi.org/10.18632/aging.100843 pp 964—973

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Rapamycin-induced metabolic defects are reversible in both lean and obese mice

Yuhong Liu, Vivian Diaz, Elizabeth Fernandez, Randy Strong, Lan Ye, Joseph A. Baur, Dudley W. Lamming, Arlan Richardson, Adam B. Salmon,

https://doi.org/10.18632/aging.100688 pp 742—754

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Centenarians as super-controls to assess the biological relevance of genetic risk factors for common age-related diseases: A proof of principle on type 2 diabetes

Paolo Garagnani, Cristina Giuliani, Chiara Pirazzini, Fabiola Olivieri, Maria Giulia Bacalini, Rita Ostan, Daniela Mari, Giuseppe Passarino, Daniela Monti, Anna Rita Bonfigli, Massimo Boemi, Antonio Ceriello, Stefano Genovese, Federica Sevini, Donata Luiselli, Paolo Tieri, Miriam Capri, Stefano Salvioli, Jan Vijg, Yousin Suh, Massimo Delledonne, Roberto Testa, Claudio Franceschi,

https://doi.org/10.18632/aging.100562 pp 373—385

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The Tellurium compound, AS101, increases SIRT1 level and activity and prevents type 2 diabetes

Meital Halperin-Sheinfeld, Asaf Gertler, Eitan Okun, Benjamin Sredni, Haim Y. Cohen,

https://doi.org/10.18632/aging.100468 pp 436—447

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Once again on rapamycin-induced insulin resistance and longevity: despite of or owing to

Mikhail V. Blagosklonny,

https://doi.org/10.18632/aging.100461 pp 350—358

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Resveratrol-activated SIRT1 in liver and pancreatic β-cells: a Janus head looking to the same direction of metabolic homeostasis

Laurène Vetterli, Pierre Maechler,

https://doi.org/10.18632/aging.100304 pp 444—449

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RasGrf1 deficiency delays aging in mice

Consuelo Borrás, Daniel Monleón, Raul López-Grueso, Juan Gambini, Leonardo Orlando, Federico V. Pallardó, Eugenio Santos, José Viña, Jaime Font de Mora,

https://doi.org/10.18632/aging.100279 pp 262—276

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Reduced mitochondrial function in obesity-associated fatty liver: SIRT3 takes on the fat

Mahua Choudhury, Karen R. Jonscher, Jacob E. Friedman,

https://doi.org/10.18632/aging.100289 pp 175—178

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Controlling SIRT1 expression by microRNAs in health and metabolic disease

Jiyoung Lee, Jongsook Kim Kemper,

https://doi.org/10.18632/aging.100184 pp 527—534

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Nutrient withdrawal rescues growth factor-deprived cells from mTOR-dependent damage

Emiliano Panieri, Gabriele Toietta, Marina Mele, Valentina Labate, Sofia Chiatamone Ranieri, Salvatore Fusco, Valentina Tesori, Annalisa Antonini, Giuseppe Maulucci, Marco De Spirito, Tommaso Galeotti, Giovambattista Pani,

https://doi.org/10.18632/aging.100183 pp 487—503

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Featured Nobel Articles

Special Collection on Diabetes

W. David Strain, Abhijit S. Agarwal, Päivi M. Paldánius,

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Pradipta Ghosh,

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Peter C. Reifsnyder, Kevin Flurkey, Austen Te, David E. Harrison,

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Pasquale Picone, Silvia Vilasi, Fabio Librizzi, Marco Contardi, Domenico Nuzzo, Luca Caruana, Sara Baldassano, Antonella Amato, Flavia Mulè, Pier Luigi San Biagio, Daniela Giacomazza, Marta Di Carlo,

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Felipe C. G. C. Reis, Jéssica L. O. L. Branquinho, Bruna B. B. Brandão, Beatriz A. A. Guerra, Ismael D. D. Silva, Andrea Frontini, Thomas Thomou, Loris Sartini, Saverio Cinti, C. Ronald Ronald Kahn, William T. T. Festuccia, Alicia J. J. Kowaltowski, Marcelo A. A. Mori,

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Corinna Ross, Adam Salmon, Randy Strong, Elizabeth Fernandez, Marty Javors, Arlan Richardson, Suzette Tardif,

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Yuhong Liu, Vivian Diaz, Elizabeth Fernandez, Randy Strong, Lan Ye, Joseph A. Baur, Dudley W. Lamming, Arlan Richardson, Adam B. Salmon,

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Meital Halperin-Sheinfeld, Asaf Gertler, Eitan Okun, Benjamin Sredni, Haim Y. Cohen,

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Mikhail V. Blagosklonny,

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Laurène Vetterli, Pierre Maechler,

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Consuelo Borrás, Daniel Monleón, Raul López-Grueso, Juan Gambini, Leonardo Orlando, Federico V. Pallardó, Eugenio Santos, José Viña, Jaime Font de Mora,

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Mahua Choudhury, Karen R. Jonscher, Jacob E. Friedman,

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Jiyoung Lee, Jongsook Kim Kemper,

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Emiliano Panieri, Gabriele Toietta, Marina Mele, Valentina Labate, Sofia Chiatamone Ranieri, Salvatore Fusco, Valentina Tesori, Annalisa Antonini, Giuseppe Maulucci, Marco De Spirito, Tommaso Galeotti, Giovambattista Pani,

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