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• Research PaperVolume 15, Issue 7pp 2395-2417

  p21 facilitates chronic lung inflammation via epithelial and endothelial cells

  Relevance score: 0.00

  Naama Levi, Nurit Papismadov, Julia Majewska, Lior Roitman, Noa Wigoda, Raya Eilam, Michael Tsoory, Ron Rotkopf, Yossi Ovadya, Hagay Akiva, Ofer Regev, Valery Krizhanovsky

  Keywords: cellular senescence, chronic lung inflammation, p21 (CDKN1A)

  Published in Aging on March 30, 2023

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• Priority Research PaperVolume 12, Issue 18pp 17800-17814

  p21 can be a barrier to ferroptosis independent of p53

  Relevance score: 0.00

  Divya Venkatesh, Brent R. Stockwell, Carol Prives

  Keywords: p21, ferroptosis, cancer, p53-independent, organ damage

  Published in Aging on September 24, 2020

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• Research PaperVolume 16, Issue 3pp 2789-2811

  Targeting PERK-ATF4-P21 axis enhances the sensitivity of osteosarcoma HOS cells to Mppα-PDT

  Relevance score: 0.00

  Shenxi Zhong, Ye Zhang, Hai Mou, Changchun Jian, Qiu Huang, Yunsheng Ou

  Keywords: MPPα-PDT, human osteosarcoma, PERK pathway, autophagy, apoptosis, p21

  Published in Aging on February 5, 2024

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• Research PaperVolume 11, Issue 24pp 12546-12567

  Sirt1-inducible deacetylation of p21 promotes cardiomyocyte proliferation

  Relevance score: 0.00

  Bing Li, Mengsha Li, Xinzhong Li, Hairui Li, Yanxian Lai, Senlin Huang, Xiang He, Xiaoyun Si, Hao Zheng, Wangjun Liao, Yulin Liao, Jianping Bin

  Keywords: cardiomyocyte proliferation, cardiac regeneration, myocardial infarction, Sirt1, p21

  Published in Aging on December 26, 2019

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• Research PaperVolume 9, Issue 5pp 1386-1403

  Transgenic autoinhibition of p21-activated kinase exacerbates synaptic impairments and fronto-dependent behavioral deficits in an animal model of Alzheimer’s disease

  Relevance score: 0.00

  Cyril Bories, Dany Arsenault, Myriam Lemire, Cyntia Tremblay, Yves De Koninck, Frédéric Calon

  Keywords: Alzheimer, p21-activated kinase, frontal cortex, 3xTg-AD mice, electrophysiology, morphology

  Published in Aging on May 16, 2017

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• Research PaperVolume 1, Issue 5pp 470-480

  Identification of single nucleotide polymorphisms in the p21 (CDKN1A) gene and correlations with longevity in the Italian population

  Relevance score: 0.00

  Silvia Gravina, Francesco Lescai, Gregory Hurteau, Graham J. Brock, Anna Saramaki, Stefano Salvioli, Claudio Franceschi, Igor B. Roninson

  Keywords: CDKN1A, single nucleotide polymorphisms, longevity

  Published in Aging on April 20, 2009

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• Research PaperVolume 12, Issue 14pp 14285-14299

  C5aR deficiency attenuates the breast cancer development via the p38/p21 axis

  Relevance score: 0.00

  Jian Chen, Zi-han Sun, Li-ying Chen, Feng Xu, Yun-pei Zhao, Gui-qing Li, Ming Tang, You Li, Quan-you Zheng, Shu-feng Wang, Xin-hua Yang, Yu-zhang Wu, Gui-lian Xu

  Keywords: breast cancer, C5a/C5aR, p38, p21

  Published in Aging on July 15, 2020

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• Research PaperVolume 12, Issue 8pp 6700-6732

  Mitochondrial nucleoid remodeling and biogenesis are regulated by the p53-p21^WAF1-PKCζ pathway in p16^INK4a-silenced cells

  Relevance score: 0.00

  Yun Yeong Lee, Yeon Seung Choi, Do Wan Kim, Jae Youn Cheong, Kye Yong Song, Min Sook Ryu, In Kyoung Lim

  Keywords: senescence, p53-p21-PKCζ activation, p16INK4a silence, mitochondria, nucleoid remodeling

  Published in Aging on April 24, 2020

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• Research PaperVolume 15, Issue 22pp 13558-13578

  Lnc-PTCHD4-AS inhibits gastric cancer through MSH2-MSH6 dimerization and ATM-p53-p21 activation

  Relevance score: 0.00

  Jingyun Wang, Yang Mi, Xiangdong Sun, Xia Xue, Huanjie Zhao, Mengfei Zhang, Baitong Hu, Ihtisham Bukhari, Pengyuan Zheng

  Keywords: gastric cancer, long non-coding RNA PTCHD4-AS, DNA mismatch repair proteins, MSH2-MSH6, cisplatin

  Published in Aging on November 27, 2023

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• Research PaperVolume 12, Issue 12pp 11386-11397

  Bone marrow mesenchymal stem cells improve thymus and spleen function of aging rats through affecting P21/PCNA and suppressing oxidative stress

  Relevance score: 0.00

  Zhihong Wang, Yun Lin, Shang Jin, Tiannan Wei, Zhihai Zheng, Weimin Chen

  Keywords: BMSCs, immune system, aging, P21/PCNA, oxidative stress

  Published in Aging on June 19, 2020

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• Research PaperVolume 12, Issue 3pp 3025-3041

  Obg-like ATPase 1 (OLA1) overexpression predicts poor prognosis and promotes tumor progression by regulating P21/CDK2 in hepatocellular carcinoma

  Relevance score: 0.00

  Shanzhou Huang, Chuanzhao Zhang, Chengjun Sun, Yuchen Hou, Yixi Zhang, Nga Lei Tam, Zekang Wang, Jia Yu, Bowen Huang, Hongkai Zhuang, Zixuan Zhou, Zuyi Ma, Zhonghai Sun, Xiaoshun He, Qi Zhou, Baohua Hou, Linwei Wu

  Keywords: HCC, OAL1, CDK2, prognosis, tumor progression

  Published in Aging on February 11, 2020

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• Research PaperVolume 12, Issue 3pp 2507-2529

  PRMT5-TRIM21 interaction regulates the senescence of osteosarcoma cells by targeting the TXNIP/p21 axis

  Relevance score: 0.00

  Yu-Hang Li, Kui-Leung Tong, Jun-Lei Lu, Jie-Bin Lin, Zhen-Yan Li, Yuan Sang, Abdelmoumin Ghodbane, Xue-Juan Gao, Man-Seng Tam, Chang-Deng Hu, Huan-Tian Zhang, Zhen-Gang Zha

  Keywords: PRMT5, TRIM21, senescence, TXNIP, p21

  Published in Aging on February 5, 2020

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• Research PaperVolume 12, Issue 24pp 26080-26094

  Postprandial triglyceride-rich lipoproteins-induced premature senescence of adipose-derived mesenchymal stem cells via the SIRT1/p53/Ac-p53/p21 axis through oxidative mechanism

  Relevance score: 0.00

  Qun-yan Xiang, Feng Tian, Xiao Du, Jin Xu, Li-yuan Zhu, Li-ling Guo, Tie Wen, You-shuo Liu, Ling Liu

  Keywords: triglyceride-rich lipoproteins, adipose-derived mesenchymal stem cells, premature senescence, SIRT1, oxidative stress

  Published in Aging on December 9, 2020

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• Research PaperVolume 12, Issue 9pp 8067-8083

  BMAL1 knockdown triggers different colon carcinoma cell fates by altering the delicate equilibrium between AKT/mTOR and P53/P21 pathways

  Relevance score: 0.00

  Yuan Zhang, Aurore Devocelle, Lucas Souza, Adlen Foudi, Sabrina Tenreira Bento, Christophe Desterke, Rachel Sherrard, Annabelle Ballesta, Rene Adam, Julien Giron-Michel, Yunhua Chang

  Keywords: BMAL1, mTOR, P53, senescence, colorectal cancer1

  Published in Aging on May 10, 2020

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• Research PaperVolume 12, Issue 8pp 6823-6851

  Intracellular Insulin-like growth factor binding protein 2 (IGFBP2) contributes to the senescence of keratinocytes in psoriasis by stabilizing cytoplasmic p21

  Relevance score: 0.00

  Laura Mercurio, Daniela Lulli, Francesca Mascia, Elena Dellambra, Claudia Scarponi, Martina Morelli, Carola Valente, Maria Luigia Carbone, Sabatino Pallotta, Giampiero Girolomoni, Cristina Albanesi, Saveria Pastore, Stefania Madonna

  Keywords: psoriasis, senescence, insulin-like growth factor binding protein 2, keratinocytes, p21CIP1/WAF1

  Published in Aging on April 17, 2020

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• Research PaperVolume 11, Issue 21pp 9689-9708

  Circular RNA circGRAMD1B inhibits gastric cancer progression by sponging miR-130a-3p and regulating PTEN and p21 expression

  Relevance score: 0.00

  Xinglong Dai, Xiong Guo, Jianjun Liu, Anqi Cheng, Xudong Peng, Lang Zha, Ziwei Wang

  Keywords: gastric cancer, circGRAMD1B, miR-130a-3p, PTEN, p21

  Published in Aging on November 13, 2019

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• Research PaperVolume 13, Issue 9pp 12514-12525

  Capsanthin induces G1/S phase arrest, erlotinib-sensitivity and inhibits tumor progression by suppressing EZH2-mediated epigenetically silencing of p21 in triple-negative breast cancer cells

  Relevance score: 0.00

  Jia-Yan Wu, Yi-Chung Chien, I-Chen Tsai, Chih-Chiang Hung, Wei-Chien Huang, Liang-Chih Liu, Yung-Luen Yu

  Keywords: capsanthin, triple-negative breast cancer (TNBC), EZH2, p21, erlotinib

  Published in Aging on May 2, 2021

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• Priority Research PaperVolume 13, Issue 10pp 13380-13392

  Cdkn1a transcript variant 2 is a marker of aging and cellular senescence

  Relevance score: 0.00

  José Alberto López-Domínguez, Sandra Rodríguez-López, Ulises Ahumada-Castro, Pierre-Yves Desprez, Maria Konovalenko, Remi-Martin Laberge, César Cárdenas, José Manuel Villalba, Judith Campisi

  Keywords: p21, p53, mouse dermal fibroblast, ionizing radiation, doxorubicin

  Published in Aging on May 25, 2021

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• Research PaperVolume 11, Issue 11pp 3832-3850

  Knockdown of angiopoietin-like 2 induces clearance of vascular endothelial senescent cells by apoptosis, promotes endothelial repair and slows atherogenesis in mice

  Relevance score: 0.00

  Laurie Caland, Pauline Labbé, Maya Mamarbachi, Louis Villeneuve, Gerardo Ferbeyre, Pierre-Emmanuel Noly, Michel Carrier, Nathalie Thorin-Trescases, Éric Thorin

  Keywords: p21, Bax/Bcl2, CD34, PAI-1, human internal mammary artery

  Published in Aging on June 11, 2019

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• Priority Research PaperVolume 12, Issue 5pp 4052-4066

  Survey of senescent cell markers with age in human tissues

  Relevance score: 0.00

  M. Laura Idda, Waverly G. McClusky, Valeria Lodde, Rachel Munk, Kotb Abdelmohsen, Martina Rossi, Myriam Gorospe

  Keywords: senescence in tissues, aging, p21, p16

  Published in Aging on March 11, 2020

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