Search

Search Results

190 results found. Results per page: [ 20 ] [ 40 ] [ 60 ] [ 80 ] [ 100 ] [ 200 ] [ 300 ]

Sort by: [ Publication Date ] [ Score ]

Direction: [ Desc ] [ Asc ]

Year of publication: [ 2026 ] [ 2025 ] [ 2024 ] [ 2023 ] [ 2022 ] [ 2021 ] [ 2020 ] [ 2019 ] [ 2018 ] [ 2017 ] [ 2016 ] [ 2015 ] [ 2014 ] [ 2013 ] [ 2012 ] [ 2011 ] [ 2010 ] [ 2009 ] [ Any ]

Page: 12345678910 of 10

• Research PerspectiveVolume 13, Issue 3pp 3167-3175

  DNA- and telomere-damage does not limit lifespan: evidence from rapamycin

  Relevance score: 0.00

  Mikhail V. Blagosklonny

  Keywords: quasi-programmed aging, hyperfunction theory, antagonistic pleiotropy, natural selection, mTOR

  Published in Aging on February 12, 2021

  Show abstract
• Research PerspectiveVolume 3, Issue 1pp 26-32

  p53 governs telomere regulation feedback too, via TRF2

  Relevance score: 0.00

  Izumi Horikawa, Kaori Fujita, Curtis C. Harris

  Keywords: telomere uncapping, p53, ubiquitin ligase, TRF2, feedback regulation

  Published in Aging on January 25, 2011

  Show abstract
• Research PaperVolume 13, Issue 4pp 4926-4945

  Functional analysis of POLD1 p.ser605del variant: the aging phenotype of MDPL syndrome is associated with an impaired DNA repair capacity

  Relevance score: 0.00

  Michela Murdocca, Paola Spitalieri, Claudia De Masi, Ion Udroiu, Jessica Marinaccio, Massimo Sanchez, Rosa Valentina Talarico, Chiara Fiorillo, Monica D’Adamo, Paolo Sbraccia, Maria Rosaria D’Apice, Giuseppe Novelli, Antonella Sgura, Federica Sangiuolo

  Keywords: MDPL syndrome, POLD1 gene, age-related disease, DNA repair, telomere damage

  Published in Aging on February 22, 2021

  Show abstract
• Research PaperVolume 1, Issue 2pp 212-218

  Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells

  Relevance score: 0.00

  Asako J. Nakamura, Christophe E. Redon, William M. Bonner, Olga A. Sedelnikova

  Keywords: DNA damage, double-strand breaks, γ-H2AX, metaphase, telomeres, tumors

  Published in Aging on February 4, 2009

  Show abstract
• EditorialVolume 2, Issue 10pp 639-642

  The telomere protein tankyrase 1 regulates DNA damage responses at telomeres

  Relevance score: 0.00

  Sandy Chang

  Published in Aging on October 20, 2010

  Show abstract
• Research PaperVolume 8, Issue 1pp 147-155

  DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age

  Relevance score: 0.00

  Mariëtte E.C. Waaijer, Eleonora Croco, Rudi G.J. Westendorp, P. Eline Slagboom, John M. Sedivy, Antonello Lorenzini, Andrea B. Maier

  Keywords: human aging, 53BP1, telomere-associated foci, micronuclei, biological age

  Published in Aging on January 30, 2016

  Show abstract
• Research PaperVolume 1, Issue 3pp 303-315

  Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice

  Relevance score: 0.00

  Luis Miguel Guachalla, Zhenyu Ju, Rafal Koziel, Guido von Figura, Zhangfa Song, Markus Fusser, Bernd Epe, Pidder Jansen-Dűrr, K. Lenhard Rudolph

  Keywords: oxidative stress, superoxide, telomere shortening, aging, DNA damage, SOD2, free radicals, stem cells

  Published in Aging on March 5, 2009

  Show abstract
• Research PaperVolume 13, Issue 4pp 6025-6040

  SIRT6 enhances telomerase activity to protect against DNA damage and senescence in hypertrophic ligamentum flavum cells from lumbar spinal stenosis patients

  Relevance score: 0.00

  Jianwei Chen, Zude Liu, Hantao Wang, Lie Qian, Zhanchun Li, Qingxin Song, Guibin Zhong

  Keywords: SIRT6, senescence, DNA damage, telomere dysfunction, telomerase activity

  Published in Aging on February 10, 2021

  Show abstract
• Research PaperVolume 12, Issue 12pp 12342-12375

  Telomere attrition and dysfunction: a potential trigger of the progeroid phenotype in nijmegen breakage syndrome

  Relevance score: 0.00

  Raneem Habib, Ryong Kim, Heidemarie Neitzel, Ilja Demuth, Krystyna Chrzanowska, Eva Seemanova, Renaldo Faber, Martin Digweed, Reinhard Voss, Kathrin Jäger, Karl Sperling, Michael Walter

  Keywords: nijmegen breakage syndrome, telomere-position effect over long distances, alternative lengthening of telomeres, nibrin, DNA repair

  Published in Aging on June 20, 2020

  Show abstract
• Research PaperVolume 2, Issue 7pp 432-444

  LIM-domain proteins TRIP6 and LPP associate with shelterin to mediate telomere protection

  Relevance score: 0.00

  Samantha A. Sheppard, Diego Loayza

  Keywords: Telomere, shelterin, POT1, LIM domain, TRIP6, LPP, p53BP1

  Published in Aging on July 14, 2010

  Show abstract
• Priority Research PaperVolume 1, Issue 7pp 608-621

  Telomere length regulates ISG15 expression in human cells

  Relevance score: 0.00

  Zhenjun Lou, Jun Wei, Harold Riethman, Joseph A. Baur, Regina Voglauer, Jerry W. Shay, Woodring E. Wright

  Keywords: telomere position effect, ISG15, aging, cancer, cell turnover, inflammation

  Published in Aging on July 17, 2009

  Show abstract
• Research PaperVolume 14, Issue 20pp 8179-8204

  Crosstalk between age accumulated DNA-damage and the SIRT1-AKT-GSK3ß axis in urine derived renal progenitor cells

  Relevance score: 0.00

  Lars Erichsen, James Adjaye

  Keywords: renal differentiation, aging, SIRT1, DNA-damage

  Published in Aging on September 24, 2022

  Show abstract
• Research PaperVolume 12, Issue 14pp 14791-14807

  MiR-185 targets POT1 to induce telomere dysfunction and cellular senescence

  Relevance score: 0.00

  Tingting Li, Zhenhua Luo, Song Lin, Chujun Li, Shenkun Dai, Haoli Wang, Junjiu Huang, Wenbin Ma, Zhou Songyang, Yan Huang

  Keywords: cellular senescence, protection of telomere 1, miR-185, telomere dysfunction, aging

  Published in Aging on July 18, 2020

  Show abstract
• Research PaperVolume 9, Issue 9pp 1957-1970

  The G-quadruplex DNA stabilizing drug pyridostatin promotes DNA damage and downregulates transcription of Brca1 in neurons

  Relevance score: 0.00

  Jose F. Moruno-Manchon, Edward C. Koellhoffer, Jayakrishnan Gopakumar, Shashank Hambarde, Nayun Kim, Louise D. McCullough, Andrey S. Tsvetkov

  Keywords: G-quadruplex, DNA damage, transcription, BRCA1, neurodegeneration

  Published in Aging on September 12, 2017

  Show abstract
• Priority Research PaperVolume 12, Issue 18pp 17761-17785

  An ordered assembly of MYH glycosylase, SIRT6 protein deacetylase, and Rad9-Rad1-Hus1 checkpoint clamp at oxidatively damaged telomeres

  Relevance score: 0.00

  Jun Tan, Xiangyu Wang, Bor-Jang Hwang, Rex Gonzales, Olivia Konen, Li Lan, A-Lien Lu

  Keywords: SIRT6, MutY homolog (MYH or MUTYH), checkpoint clamp Rad9/Rad1/Hus1 (9-1-1), DNA damage response, telomeres

  Published in Aging on September 29, 2020

  Show abstract
• Research PaperVolume 11, Issue 21pp 9829-9845

  Slower rates of accumulation of DNA damage in leukocytes correlate with longer lifespans across several species of birds and mammals

  Relevance score: 0.00

  Kurt Whittemore, Eva Martínez-Nevado, Maria A. Blasco

  Keywords: species, lifespan, DNA damage, short telomeres

  Published in Aging on November 15, 2019

  Show abstract
• Research PaperVolume 11, Issue 7pp 1965-1976

  SIRT6 participates in the quality control of aged oocytes via modulating telomere function

  Relevance score: 0.00

  Juan Ge, Congyang Li, Chunling Li, Zhenyue Huang, Juan Zeng, Longsen Han, Qiang Wang

  Keywords: aging, sirtuin, oocyte quality, telomere, embryo development

  Published in Aging on March 29, 2019

  Show abstract
• Research PaperVolume 9, Issue 4pp 1219-1232

  The differential spatiotemporal expression pattern of shelterin genes throughout lifespan

  Relevance score: 0.00

  Kay-Dietrich Wagner, Yilin Ying, Waiian Leong, Jie Jiang, Xuefei Hu, Yi Chen, Jean-François Michiels, Yiming Lu, Eric Gilson, Nicole Wagner, Jing Ye

  Keywords: shelterin, telomere, brain aging, development

  Published in Aging on April 17, 2017

  Show abstract
• Research PaperVolume 5, Issue 1pp 3-17

  Structural and functional association of androgen receptor with telomeres in prostate cancer cells

  Relevance score: 0.00

  Junying Zhou, Michelle Richardson, Vidyavathi Reddy, Mani Menon, Evelyn R. Barrack, G. Prem-Veer Reddy, Sahn-Ho Kim

  Keywords: Androgen receptor, telomeres, fragile telomeres, Casodex, DNA damage, genomic instability, prostate cancer

  Published in Aging on January 29, 2013

  Show abstract
• Research PaperVolume 8, Issue 9pp 2222-2231

  Specific premature epigenetic aging of cartilage in osteoarthritis

  Relevance score: 0.00

  Laura Vidal-Bralo, Yolanda Lopez-Golan, Antonio Mera-Varela, Ignacio Rego-Perez, Steve Horvath, Yuhua Zhang, Álvaro del Real, Guangju Zhai, Francisco J. Blanco, Jose A. Riancho, Juan J. Gomez-Reino, Antonio Gonzalez

  Keywords: osteoarthritis, biological age, epigenetics, DNA methylation, telomere length shortening

  Published in Aging on September 28, 2016

  Show abstract