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• Research PaperVolume 9, Issue 1pp 114-132

  Induction of fibroblast senescence generates a non-fibrogenic myofibroblast phenotype that differentially impacts on cancer prognosis

  Relevance score: 0.00

  Massimiliano Mellone, Christopher J. Hanley, Steve Thirdborough, Toby Mellows, Edwin Garcia, Jeongmin Woo, Joanne Tod, Steve Frampton, Veronika Jenei, Karwan A. Moutasim, Tasnuva D. Kabir, Peter A Brennan, Giulia Venturi, Kirsty Ford, Nicolas Herranz, Kue Peng Lim, James Clarke, Daniel W. Lambert, Stephen S. Prime, Timothy J. Underwood, Pandurangan Vijayanand, Kevin W. Eliceiri, Christopher Woelk, Emma V. King, Jesus Gil, Christian H. Ottensmeier, Gareth J. Thomas

  Keywords: tumor microenvironment, myofibroblasts, senescence, collagen, extracellular matrix, senescent fibroblasts

  Published in Aging on December 15, 2016

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• Research PaperVolume 8, Issue 5pp 841-847

  Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan

  Relevance score: 0.00

  Alison Patrick, Michael Seluanov, Chaewon Hwang, Jonathan Tam, Tanya Khan, Ari Morgenstern, Lauren Wiener, Juan M. M. Vazquez, Hiba Zafar, Robert Wen, Malika Muratkalyeva, Katherine Doerig, Maria Zagorulya, Lauren Cole, Sophia Catalano, Aliny AB AB Lobo Ladd, A. Augusto Augusto Coppi, Yüksel Coşkun, Xiao Tian, Julia Ablaeva, Eviatar Nevo, Vadim N. N. Gladyshev, Zhengdong D. D. Zhang, Jan Vijg, Andrei Seluanov, Vera Gorbunova

  Keywords: fibroblasts, oxygen, senescence, human, rodents

  Published in Aging on May 7, 2016

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• Research PaperVolume 12, Issue 2pp 1910-1927

  Effect of antioxidants on the H2O2-induced premature senescence of human fibroblasts

  Relevance score: 0.00

  Natalia Pieńkowska, Grzegorz Bartosz, Monika Pichla, Michalina Grzesik-Pietrasiewicz, Martyna Gruchala, Izabela Sadowska-Bartosz

  Keywords: stress-induced premature senescence, fibroblasts, antioxidants, hydrogen peroxide

  Published in Aging on January 21, 2020

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• Research PaperVolume 13, Issue 14pp 17978-18005

  HDAC2 and 7 down-regulation induces senescence in dermal fibroblasts

  Relevance score: 0.00

  Céline Warnon, Karim Bouhjar, Noëlle Ninane, Mathilde Verhoyen, Antoine Fattaccioli, Maude Fransolet, Catherine Lambert de Rouvroit, Yves Poumay, Géraldine Piel, Denis Mottet, Florence Debacq-Chainiaux

  Keywords: histone deacetylases, senescence, fibroblasts, SAHA, SASP

  Published in Aging on July 12, 2021

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• Research PaperVolume 11, Issue 2pp 573-589

  Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro

  Relevance score: 0.00

  Zhirui Fan, Lifeng Li, Xiaoli Li, Meng Zhang, Mengmeng Dou, Jing Zhao, Jing Cao, Xiaoming Deng, Mingzhi Zhang, Huixiang Li, Zhenhe Suo

  Keywords: anti-senescence, fumarate hydratase, rat lung fibroblasts

  Published in Aging on January 21, 2019

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• Research PaperVolume 9, Issue 5pp 1404-1413

  Diffuse colonies of human skin fibroblasts in relation to cellular senescence and proliferation

  Relevance score: 0.00

  Vadim Zorin, Alla Zorina, Nadezhda Smetanina, Pavel Kopnin, Ivan V. Ozerov, Sergey Leonov, Artur Isaev, Dmitry Klokov, Andreyan N. Osipov

  Keywords: skin fibroblasts, сlonogenic assay, proliferation, cellular senescence, β-galactosidase

  Published in Aging on May 16, 2017

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• ErratumVolume 7, Issue 11pp 1022-1022

  Erratum: Cellular senescence-like features of lung fibroblasts derived from idiopathic pulmonary fibrosis patients

  Relevance score: 0.00

  Hagai Yanai, Albert Shteinberg, Ziv Porat, Arie Budovsky, Alex Braiman, Rolf Zeische, Vadim E. Fraifeld

  Keywords: cellular senescence, idiopathic pulmonary fibrosis, fibroblasts, cancer

  Published in Aging on September 22, 2015

• Research PaperVolume 7, Issue 9pp 664-672

  Cellular senescence-like features of lung fibroblasts derived from idiopathic pulmonary fibrosis patients

  Relevance score: 0.00

  Hagai Yanai, Albert Shteinberg, Ziv Porat, Arie Budovsky, Alex Braiman, Rolf Zeische, Vadim E. Fraifeld

  Keywords: cellular senescence, idiopathic pulmonary fibrosis, fibroblasts, cancer

  Published in Aging on September 22, 2015

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• Research PaperVolume 7, Issue 3pp 152-166

  Serum from calorie-restricted animals delays senescence and extends the lifespan of normal human fibroblasts in vitro

  Relevance score: 0.00

  Rafael de Cabo, Lijuan Liu, Ahmed Ali, Nathan Price, Jing Zhang, Mingyi Wang, Edward Lakatta, Pablo M. Irusta

  Keywords: human diploid fibroblasts, senescence, caloric restriction, lifespan extension, SIRT1, aging

  Published in Aging on January 13, 2015

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• Research PaperVolume 18, Issue 1pp 340-368

  Stage-dependent transcriptomic changes in human dermal fibroblast senescence model

  Relevance score: 0.00

  Michiko Kudo, Ryo Yonezawa, Hideaki Mizobata, Shigeharu Kinoshita, Shuichi Asakawa

  Keywords: cellular senescence, dermal fibroblasts, transcriptome analysis, immune–inflammatory signaling, aging biomarkers

  Published in Aging on April 10, 2026

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• Research PerspectiveVolume 2, Issue 3pp 160-165

  How to become immortal: let MEFs count the ways

  Relevance score: 0.00

  Adam Odell, Jon Askham, Catherine Whibley, Monica Hollstein

  Keywords: murine embryonic fibroblasts (MEFs), senescence, p53, p19/ARF, Hupki

  Published in Aging on March 18, 2010

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• Research PaperVolume 11, Issue 13pp 4536-4546

  Spontaneous γH2AX foci in human dermal fibroblasts in relation to proliferation activity and aging

  Relevance score: 0.00

  Vadim Zorin, Anna Grekhova, Margarita Pustovalova, Alla Zorina, Nadezhda Smetanina, Natalia Vorobyeva, Pavel Kopnin, Ilmira Gilmutdinova, Alexey Moskalev, Andreyan N. Osipov, Sergey Leonov

  Keywords: dermal fibroblasts, aging, γH2AX foci, proliferation, cellular senescence, β‐galactosidase, сlonogenic assay

  Published in Aging on July 9, 2019

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• Research PaperVolume 11, Issue 9pp 2889-2897

  c-Met as a new marker of cellular senescence

  Relevance score: 0.00

  Maria Boichuck, Jonathan Zorea, Moshe Elkabets, Marina Wolfson, Vadim E. Fraifeld

  Keywords: cellular senescence, c-Met, Akt, Stat3, human dermal and pulmonary fibroblasts

  Published in Aging on May 13, 2019

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• Research PaperVolume 16, Issue 9pp 7523-7534

  Cell type-dependent modulation of senescence features using Weo electrolyzed water

  Relevance score: 0.00

  Brenda L. Court-Vazquez, Shirley A. Arroyo-Vizcarrondo, Jonathan A. Poli, Lara Nyman, Kelly Halderman, Anthony Ginter, Pierre-Yves Desprez

  Keywords: cellular senescence, senescence-associated secretory phenotype, oxidative stress, lung fibroblasts, breast cancer cells, senomorphic

  Published in Aging on April 30, 2024

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• Research PaperVolume 14, Issue 7pp 2966-2988

  Downregulation of IGFBP5 contributes to replicative senescence via ERK2 activation in mouse embryonic fibroblasts

  Relevance score: 0.00

  Iyori Nojima, Ryusuke Hosoda, Yuki Toda, Yoshiki Saito, Naohiro Ueda, Kouhei Horimoto, Naotoshi Iwahara, Yoshiyuki Horio, Atsushi Kuno

  Keywords: IGFBP5, replicative senescence, mouse embryonic fibroblasts, ERK2, ERK1

  Published in Aging on April 4, 2022

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• Research PaperVolume 4, Issue 6pp 431-435

  Replicatively senescent cells are arrested in G1 and G2 phases

  Relevance score: 0.00

  Zhiyong Mao, Zhonghe Ke, Vera Gorbunova, Andrei Seluanov

  Keywords: replicative senescence, aging, cell cycle, human fibroblasts

  Published in Aging on June 28, 2012

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• Research PaperVolume 11, Issue 11pp 3731-3749

  Nectandrin B-mediated activation of the AMPK pathway prevents cellular senescence in human diploid fibroblasts by reducing intracellular ROS levels

  Relevance score: 0.00

  Hyun-Jin Jang, Kyeong Eun Yang, Won Keun Oh, Song-I Lee, In-Hu Hwang, Kyung-Tae Ban, Hwa-Seung Yoo, Jong-Soon Choi, Eui-Ju Yeo, Ik-Soon Jang

  Keywords: Nectandrin B, cellular senescence, reactive oxygen species, AMP-activated protein kinase, human diploid fibroblasts

  Published in Aging on June 14, 2019

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• Research PaperVolume 4, Issue 11pp 823-842

  Depletion of nuclear histone H2A variants is associated with chronic DNA damage signaling upon drug-evoked senescence of human somatic cells

  Relevance score: 0.00

  Mary F. Lopez, James Tollervey, Bryan Krastins, Alejandra Garces, David Sarracino, Amol Prakash, Maryann Vogelsang, Glenn Geesman, Augusto Valderrama, I. King Jordan, Victoria V. Lunyak

  Keywords: γH2A.X, DNA damage, senescence, LS-MS analysis, quantitative proteomic, SRM, histone H2A family, chromatin, DNA repair, HCA2 primary fibroblasts, epigenetics

  Published in Aging on December 6, 2012

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• Research PaperVolume 13, Issue 9pp 12308-12333

  Shikimic acid protects skin cells from UV-induced senescence through activation of the NAD+-dependent deacetylase SIRT1

  Relevance score: 0.00

  Alfredo Martínez-Gutiérrez, Irene Fernández-Duran, Anna Marazuela-Duque, Nicolás G. Simonet, Ibraheem Yousef, Immaculada Martínez-Rovira, Josefina Martínez-Hoyos, Alejandro Vaquero

  Keywords: SIRT1, senescence, human dermal fibroblasts, UV irradiation, shikimic acid

  Published in Aging on April 26, 2021

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• Research PaperVolume 5, Issue 6pp 460-473

  Identification of microRNAs dysregulated in cellular senescence driven by endogenous genotoxic stress

  Relevance score: 0.00

  Lolita S. Nidadavolu, Laura J. Niedernhofer, Saleem A. Khan

  Keywords: MicroRNA, aging, cellular senescence, DNA repair, mouse embryonic fibroblasts

  Published in Aging on June 28, 2013

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