Online ISSN: 1945-4589
Learn about our FREE Post-Publication Promotion Services

Special Collection on Longevity and Rapamycin


PDF EPUB

iBooks, GooglePlay Books and Kindle Fire eReaders are the best way to view Epub formats

Explore This Issue

Metabolic consequences of long-term rapamycin exposure on common marmoset monkeys (Callithrix jacchus)

Corinna Ross, Adam Salmon, Randy Strong, Elizabeth Fernandez, Marty Javors, Arlan Richardson, Suzette Tardif,
https://doi.org/10.18632/aging.100843 pp 964—973
View Abstract PDF Full-Text How to Cite

Rapamycin-induced metabolic defects are reversible in both lean and obese mice

Yuhong Liu, Vivian Diaz, Elizabeth Fernandez, Randy Strong, Lan Ye, Joseph A. Baur, Dudley W. Lamming, Arlan Richardson, Adam B. Salmon,
https://doi.org/10.18632/aging.100688 pp 742—754
View Abstract PDF Full-Text How to Cite

Target of rapamycin signalling mediates the lifespan-extending effects of dietary restriction by essential amino acid alteration

Sahar Emran, Mingyao Yang, Xiaoli He, Jelle Zandveld, Matthew D. W. Piper,
https://doi.org/10.18632/aging.100665 pp 390—398
View Abstract PDF Full-Text How to Cite

Rapamycin in preventive (very low) doses

Roman V. Kondratov, Anna A. Kondratova,
https://doi.org/10.18632/aging.100645 pp 158—159
PDF How to Cite

Immunostimulatory activity of lifespan-extending agents

José Manuel Bravo-San Pedro, Laura Senovilla,
https://doi.org/10.18632/aging.100619 pp 793—801
View Abstract PDF Full-Text How to Cite

Rapamycin extends life- and health span because it slows aging

Mikhail V. Blagosklonny,
https://doi.org/10.18632/aging.100591 pp 592—598
View Abstract PDF Full-Text How to Cite

Prolonged Rapamycin treatment led to beneficial metabolic switch

Yimin Fang, Andrzej Bartke,
https://doi.org/10.18632/aging.100554 pp 328—329
PDF How to Cite

Rapamycin extends life span of Rb1+/− mice by inhibiting neuroendocrine tumors

Carolina B. Livi, Rulon L. Hardman, Barbara A. Christy, Sherry G. Dodds, Diane Jones, Charnae Williams, Randy Strong, Alex Bokov, Martin A. Javors, Yuji Ikeno, Gene Hubbard, Paul Hasty, Zelton Dave Sharp,
https://doi.org/10.18632/aging.100533 pp 100—110
View Abstract PDF Full-Text How to Cite

Rapamycin as longevity enhancer and cancer preventative agent in the context of p53 deficiency

Lawrence A. Donehower,
https://doi.org/10.18632/aging.100494 pp 660—661
PDF How to Cite

Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/− mice

Elena A. Komarova, Marina P. Antoch, Liliya R. Novototskaya, Olga B. Chernova, Geraldine Paszkiewicz, Olga V. Leontieva, Mikhail V. Blagosklonny, Andrei V. Gudkov,
https://doi.org/10.18632/aging.100498 pp 709—714
View Abstract PDF Full-Text How to Cite

New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53−/− mice by delaying carcinogenesis

Maria Comas, Ilia Toshkov, Karen K. Kuropatwinski, Olga B. Chernova, Alexander Polinsky, Mikhail V. Blagosklonny, Andrei V. Gudkov, Marina P. Antoch,
https://doi.org/10.18632/aging.100496 pp 715—722
View Abstract PDF Full-Text How to Cite

How to save Medicare: the anti-aging remedy

Mikhail V. Blagosklonny,
https://doi.org/10.18632/aging.100479 pp 547—552
View Abstract PDF Full-Text How to Cite

Once again on rapamycin-induced insulin resistance and longevity: despite of or owing to

Mikhail V. Blagosklonny,
https://doi.org/10.18632/aging.100461 pp 350—358
View Abstract PDF Full-Text How to Cite

Rapamycin increases oxidative stress response gene expression in adult stem cells

Amber E. Kofman, Margeaux R. McGraw, Christopher J. Payne,
https://doi.org/10.18632/aging.100451 pp 279—289
View Abstract PDF Full-Text How to Cite

The implication of Sir2 in replicative aging and senescence in Saccharomyces cerevisiae

Cheol Woong Ha, Won-Ki Huh,
https://doi.org/10.18632/aging.100299 pp 319—324
View Abstract PDF Full-Text How to Cite

Potential of mTOR inhibitors for the treatment of subependymal giant cell astrocytomas in tuberous sclerosis complex

Philippe Major,
https://doi.org/10.18632/aging.100298 pp 189—191
View Abstract PDF How to Cite

Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level

Alexander A. Goldberg, Pavlo Kyryakov, Simon D. Bourque, Vladimir I. Titorenko,
https://doi.org/10.18632/aging.100186 pp 461—470
View Abstract PDF Full-Text How to Cite

Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes

Alexander A. Goldberg, Vincent R. Richard, Pavlo Kyryakov, Simon D. Bourque, Adam Beach, Michelle T. Burstein, Anastasia Glebov, Olivia Koupaki, Tatiana Boukh-Viner, Christopher Gregg, Mylène Juneau, Ann M. English, David Y. Thomas, Vladimir I. Titorenko,
https://doi.org/10.18632/aging.100168 pp 393—414
View Abstract PDF Full-Text How to Cite

Why men age faster but reproduce longer than women: mTOR and evolutionary perspectives

Mikhail V. Blagosklonny,
https://doi.org/10.18632/aging.100149 pp 265—273
View Abstract PDF Full-Text How to Cite

Why human lifespan is rapidly increasing: solving "longevity riddle" with "revealed-slow-aging" hypothesis

Mikhail V. Blagosklonny,
https://doi.org/10.18632/aging.100139 pp 177—182
View Abstract PDF Full-Text How to Cite

Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density

Yong Pan, Gerald S. Shadel,
https://doi.org/10.18632/aging.100016 pp 131—145
View Abstract PDF Full-Text How to Cite

Macronutrient balance and lifespan

Stephen J. Simpson, David Raubenheimer,
https://doi.org/10.18632/aging.100098 pp 875—880
View Abstract PDF Full-Text How to Cite

The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1

Gino Heeren, Mark Rinnerthaler, Peter Laun, Phyllis von Seyerl, Sonja Kössler, Harald Klinger, Stefanie Jarolim, Birgit Simon-Nobbe, Matthias Hager, Christoph Schüller, Didac Carmona-Gutierrez, Lore Breitenbach-Koller, Christoph Mück, Pidder Jansen-Dürr, Alfredo Criollo, Guido Kroemer, Frank Madeo, Michael Breitenbach,
https://doi.org/10.18632/aging.100065 pp 622—636
View Abstract PDF Full-Text How to Cite