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Online ISSN: 1945-4589
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09-08-2021
Aging-US published a Special Collection on Eye Disease which included " Role of Citicoline in an in vitro AMD model " which reported that citicoline is the exogenous form of the nootropic, Cytidine 5'-diphosphate-choline that exerts its neuroprotective effects in the brain as well as in the eye. Citicoline alleviates…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " Loss of NAMPT in aging retinal pigment epithelium reduces NAD+ availability and promotes cellular senescence " which reported that retinal pigment epithelium performs numerous functions critical to retinal health and visual function. Here, the…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " Abnormalities of saccadic eye movements in dementia due to Alzheimer’s disease and mild cognitive impairment " which reported that there is increasing evidence that people in the early stages of Alzheimer’s disease have subtle impairments in…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " miR-106b suppresses pathological retinal angiogenesis " which reported that microRNAs are small non-coding RNAs that post-transcriptionally regulate gene expression. Here, the authors show that expression of the miR-106b-25 cluster is negatively…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included "Suppressing endoplasmic reticulum stress-related autophagy attenuates retinal light injury" which reported that in this study, oxidative stress, endoplasmic reticulum stress and autophagy caused by light exposure were evaluated in vitro and in…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration " and reported that AMD is a major unmet medical need as it is estimated that more than 20 million patients will be affected by 2050 in the US alone. STGD is…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " Exosomes derived from BDNF-expressing 293T attenuate ischemic retinal injury in vitro and in vivo " which reported that this study investigated whether exosomes derived from BDNF-expressing 293T cells can be internalized by ischemic retinal cells…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " Systemic administration of the di-apocarotenoid norbixin (BIO201) is neuroprotective, preserves photoreceptor function and inhibits A2E and lipofuscin accumulation in animal models of age-related macular degeneration and Stargardt disease " which…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " Immunological analyses reveal an immune subtype of uveal melanoma with a poor prognosis " which reported that uveal melanoma is an aggressive intraocular malignancy that often exhibits low immunogenicity. Metastatic uveal Melanoma samples…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " Loss of macroH2A1 decreases mitochondrial metabolism and reduces the aggressiveness of uveal melanoma cells " which reported that uveal melanoma (UM) is the most common primary intraocular tumour in adults. Most accurate prognostic factor of UM is…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " Development and validation of an immune and stromal prognostic signature in uveal melanoma to guide clinical therapy " which reported that the tumor microenvironment is known to play an important role in uveal melanoma. Reliable prognostic…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " ALKBH5-mediated m6A demethylation of FOXM1 mRNA promotes progression of uveal melanoma " which reported that ALKBH5, a key component of the N6-methyladenosine (m6A) methyltransferase complex, was significantly elevated in uveal melanoma cell lines…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " Involvement of adiponectin in age-related increases in tear production in mice " which reported that the infiltration of lymphocytes into the lacrimal glands occurs with age, and age-related increases in tear production have also been observed in…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " A comprehensive evaluation of 181 reported CHST6 variants in patients with macular corneal dystrophy " which reported that macular corneal dystrophy is an autosomal recessive disease featured by bilateral progressive stromal clouding and loss of…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " Pineal gland volume is associated with prevalent and incident isolated rapid eye movement sleep behavior disorder " which reported that pineal gland volume may be associated with the risk of isolated rapid eye movement (REM) sleep behavior…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " ALDH2 protects naturally aged mouse retina via inhibiting oxidative stress-related apoptosis and enhancing unfolded protein response in endoplasmic reticulum " which reported that during the process of aging, the retina exhibits chronic oxidative…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " Exploration of age-related mitochondrial dysfunction and the anti-aging effects of resveratrol in zebrafish retina " which reported that resveratrol was shown to not only increase mitochondrial quality and function, but also to suppress Akt/mTOR…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " Long-term intake of Lactobacillus paracasei KW3110 prevents age-related chronic inflammation and retinal cell loss in physiologically aged mice " which reported that age-related chronic inflammation is a major risk factor for the incidence and…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells – implication in subretinal immune privilege in the aging eye " which reported that this study aimed to understand how complement expression…
08-22-2021
BUFFALO, NY-August 20, 2021 – Aging is indexed by Web of Science: Science Citation Index Expanded (abbreviated as Aging‑US). In June 2021, Web of Science (Clarivate Analytics) released their 2020 JCR Impact Factor. Aging is pleased to report that our 2020 impact factor is 5.682 . This number has increased from last…