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Page: 12 of 2

• EditorialVolume 8, Issue 4pp 567-568

  Repurposing of FDA-approved drugs against cancer – focus on metastasis

  Relevance score: 0.00

  Béla Ozsvári, Rebecca Lamb, Michael P. Lisanti

  Keywords: tumor metastasis, repurposing, antibiotics, aspirin

  Published in Aging on April 2, 2016

• Research PaperVolume 14, Issue 23pp 9466-9483

  Identification of natural products and FDA-approved drugs for targeting cancer stem cell (CSC) propagation

  Relevance score: 0.00

  Gloria Bonuccelli, Federica Sotgia, Michael P. Lisanti

  Keywords: cancer stem cells, drug screening, natural compounds, FDA approved drugs, mammospheres

  Published in Aging on December 1, 2022

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• Research PaperVolume 14, Issue 3pp 1448-1472

  Screening of antibacterial compounds with novel structure from the FDA approved drugs using machine learning methods

  Relevance score: 0.00

  Wen-Xing Li, Xin Tong, Peng-Peng Yang, Yang Zheng, Ji-Hao Liang, Gong-Hua Li, Dahai Liu, Dao-Gang Guan, Shao-Xing Dai

  Keywords: antibacterial compound, drug repositioning, machine learning, structural similarity, virtual screening

  Published in Aging on February 12, 2022

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• Research PaperVolume 13, Issue 5pp 6258-6272

  Screening potential FDA-approved inhibitors of the SARS-CoV-2 major protease 3CL^pro through high-throughput virtual screening and molecular dynamics simulation

  Relevance score: 0.00

  Wen-Shan Liu, Han-Gao Li, Chuan-Hua Ding, Hai-Xia Zhang, Rui-Rui Wang, Jia-Qiu Li

  Keywords: SARS-CoV-2, COVID-19, Indinavir, molecular docking, molecular dynamics simulation

  Published in Aging on March 7, 2021

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• Research PaperVolume 10, Issue 11pp 3294-3307

  Azithromycin and Roxithromycin define a new family of “senolytic” drugs that target senescent human fibroblasts

  Relevance score: 0.00

  Bela Ozsvari, John R. Nuttall, Federica Sotgia, Michael P. Lisanti

  Keywords: drug repurposing, aging, senescence, senolytic drugs, antibiotics, azithromycin, roxithromycin

  Published in Aging on November 14, 2018

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• Research PerspectiveVolume 12, Issue 8pp 6511-6517

  COVID-19 and chronological aging: senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection?

  Relevance score: 0.00

  Camillo Sargiacomo, Federica Sotgia, Michael P. Lisanti

  Keywords: COVID-19, corona virus, aging, senescence, senolytic drug therapy, prevention, viral replication, drug repurposing, antibiotic, Azithromycin, Hydroxy-chloroquine, Rapamycin, Doxycycline, Quercetin

  Published in Aging on March 30, 2020

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• Research PaperVolume 11, Issue 17pp 6691-6713

  PU-91 drug rescues human age-related macular degeneration RPE cells; implications for AMD therapeutics

  Relevance score: 0.00

  Sonali Nashine, Sudhakar R. Subramaniam, Marilyn Chwa, Anthony Nesburn, Baruch D. Kuppermann, Howard Federoff, M. Cristina Kenney

  Keywords: age-related macular degeneration (AMD), RPE, PGC-1α, mitochondria, FDA-approved drugs

  Published in Aging on September 2, 2019

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• EditorialVolume 8, Issue 11pp 2609-2610

  Biocomputing drug repurposing toward targeted therapies

  Relevance score: 0.00

  Luca Cardone

  Keywords: oncogenes, PI3K-dependent pathways, gene expression signatures, drugs network, FDA-approved drugs

  Published in Aging on November 30, 2016

• Research PaperVolume 15, Issue 24pp 15557-15577

  Exploring the effect and mechanism of Aloin A against cancer cachexia-induced muscle atrophy via network pharmacology, molecular docking, molecular dynamics and experimental validation

  Relevance score: 0.00

  Awaguli Dawuti, Lisha Ma, Xueyan An, Jiawei Guan, Changdong Zhou, Linyun He, Yue Xu, Bo Han, Abudumijiti Abulizi

  Keywords: Aloin A, cancer cachexia-induced muscle atrophy, network pharmacology, molecular docking, molecular dynamics, mice

  Published in Aging on December 29, 2023

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• Research PaperVolume 12, Issue 6pp 4727-4741

  Metformin coordinates osteoblast/osteoclast differentiation associated with ischemic osteonecrosis

  Relevance score: 0.00

  See-Hyoung Park, Mi-Ae Kang, Young Jae Moon, Kyu Yun Jang, Jung Ryul Kim

  Keywords: metformin, angiopoietin 1, ischemic osteonecrosis, osteoblastic differentiation

  Published in Aging on February 11, 2020

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• Research PaperVolume 13, Issue 10pp 14001-14014

  Adalimumab ameliorates memory impairments and neuroinflammation in chronic cerebral hypoperfusion rats

  Relevance score: 0.00

  Jing-Jing Xu, Si Guo, Rui Xue, Lin Xiao, Jun-Na Kou, Yu-Qiong Liu, Jun-Ya Han, Jing-Jie Fu, Na Wei

  Keywords: adalimumab, vascular dementia, neuroinflammation

  Published in Aging on May 24, 2021

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• Research PaperVolume 8, Issue 9pp 2081-2099

  Age-related hearing loss: prevention of threshold declines, cell loss and apoptosis in spiral ganglion neurons

  Relevance score: 0.00

  Robert D. Frisina, Bo Ding, Xiaoxia Zhu, Joseph P. Walton

  Keywords: aging, neuroscience, hearing loss, drug discovery, auditory system, neurodegeneration

  Published in Aging on September 23, 2016

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• Research PaperVolume 12, Issue 6pp 5300-5317

  Verapamil extends lifespan in Caenorhabditis elegans by inhibiting calcineurin activity and promoting autophagy

  Relevance score: 0.00

  Wenwen Liu, Huiling Lin, Zhifan Mao, Lanxin Zhang, Keting Bao, Bei Jiang, Conglong Xia, Wenjun Li, Zelan Hu, Jian Li

  Keywords: verapamil, Caenorhabditis elegans, anti-aging, cell senescence, autophagy

  Published in Aging on March 24, 2020

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• Research PerspectiveVolume 6, Issue 9pp 718-730

  Translational Geroscience: Emphasizing function to achieve optimal longevity

  Relevance score: 0.00

  Douglas R. Seals, Simon Melov

  Keywords: aging, healthspan, lifespan, physiology, biomedical research

  Published in Aging on August 10, 2014

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• Research PaperVolume 11, Issue 8pp 2202-2216

  Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs)

  Relevance score: 0.00

  Marco Fiorillo, Fanni Tóth, Federica Sotgia, Michael P. Lisanti

  Keywords: Doxycycline, Azithromycin, Vitamin C, combination therapy, mitochondrial ATP depletion, glycolysis

  Published in Aging on April 19, 2019

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• Research PaperVolume 8, Issue 8pp 1593-1606

  Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs)

  Relevance score: 0.00

  Marco Fiorillo, Rebecca Lamb, Herbert B. B. Tanowitz, Anna Rita Rita Cappello, Ubaldo E. E. Martinez-Outschoorn, Federica Sotgia, Michael P. P. Lisanti

  Keywords: bedaquiline, mitochondria, tumor-initiating cells (TICs), cancer stem-like cells (CSCs), drug repurposing

  Published in Aging on June 22, 2016

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• Research PaperVolume 9, Issue 11pp 2245-2268

  Towards natural mimetics of metformin and rapamycin

  Relevance score: 0.00

  Alexander Aliper, Leslie Jellen, Franco Cortese, Artem Artemov, Darla Karpinsky-Semper, Alexey Moskalev, Andrew G. Swick, Alex Zhavoronkov

  Keywords: geroprotector, metformin, rapamycin, deep learning, natural, nutraceutical, compound screening

  Published in Aging on November 15, 2017

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• Research PaperVolume 15, Issue 23pp 13581-13592

  Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema

  Relevance score: 0.00

  Alberta Palazzo, Gabriela Makulyte, Delphine Goerhig, Jean-Jacques Médard, Vincent Gros, François Trottein, Serge Adnot, David Vindrieux, Jean-Michel Flaman, David Bernard

  Keywords: senolytic, cigarette smoke, lung disease, cellular senescence, calcium channel

  Published in Aging on December 12, 2023

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• Research PaperVolume 13, Issue 17pp 21364-21384

  Deferoxamine accelerates endothelial progenitor cell senescence and compromises angiogenesis

  Relevance score: 0.00

  Yi-Nan Lee, Hsueh-Hsiao Wang, Cheng-Huang Su, Hsin-I Lee, Yen-Hung Chou, Chin-Ling Hsieh, Wen-Ting Liu, Kuo-Tung Shu, Kai-Ting Chang, Hung-I Yeh, Yih-Jer Wu

  Keywords: senescence, deferoxamine, angiogenesis, endothelial progenitor cell

  Published in Aging on September 11, 2021

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• Research PaperVolume 13, Issue 8pp 10866-10890

  Pharmacologic activation of autophagy without direct mTOR inhibition as a therapeutic strategy for treating dry macular degeneration

  Relevance score: 0.00

  Qitao Zhang, Feriel Presswalla, Robin R. Ali, David N. Zacks, Debra A. Thompson, Jason ML. Miller

  Keywords: age-related macular degeneration (AMD), drusen, lipofuscin, retinal pigment epithelium (RPE), autophagy

  Published in Aging on April 19, 2021

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