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Page: 12 of 2

• Priority Research PaperVolume 1, Issue 11pp 903-936

  Drosophila melanogaster p53 has developmental stage-specific and sex-specific effects on adult life span indicative of sexual antagonistic pleiotropy

  Relevance score: 0.00

  Morris Waskar, Gary N. Landis, Jie Shen, Christina Curtis, Kevin Tozer, Diana Abdueva, Dmitriy Skvortsov, Simon Tavaré, John Tower

  Keywords: aging, sexual conflict, Geneswitch, maternal effects, tumor suppressor

  Published in Aging on October 27, 2009

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• Research PaperVolume 15, Issue 20pp 10915-10937

  The Saccharomyces cerevisiae acetyltransferase Gcn5 exerts antagonistic pleiotropic effects on chronological ageing

  Relevance score: 0.00

  Kaiqiang Li, Gabriele Mocciaro, Jules L. Griffin, Nianshu Zhang

  Keywords: Gcn5, SAGA, Hda1, chronological lifespan, antagonistic pleiotropy

  Published in Aging on October 23, 2023

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• EditorialVolume 9, Issue 9pp 1953-1954

  Inhibition of neuronal autophagy mediates longevity

  Relevance score: 0.00

  Jonathan Byrne, Thomas Wilhelm, Holger Richly

  Keywords: aging, antagonistic pleiotropy, autophagy, C. elegans, neurodegeneration

  Published in Aging on September 30, 2017

• Research PaperVolume 7, Issue 1pp 53-69

  The progesterone antagonist mifepristone/RU486 blocks the negative effect on life span caused by mating in female Drosophila

  Relevance score: 0.00

  Gary N. Landis, Matthew P. Salomon, Daniel Keroles, Nicholas Brookes, Troy Sekimura, John Tower

  Keywords: aging, sexual antagonistic pleiotropy, sexual conflict, life span trade-off

  Published in Aging on January 15, 2015

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• Research PerspectiveVolume 13, Issue 3pp 3167-3175

  DNA- and telomere-damage does not limit lifespan: evidence from rapamycin

  Relevance score: 0.00

  Mikhail V. Blagosklonny

  Keywords: quasi-programmed aging, hyperfunction theory, antagonistic pleiotropy, natural selection, mTOR

  Published in Aging on February 12, 2021

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• Research PaperVolume 9, Issue 1pp 68-97

  Effects of an unusual poison identify a lifespan role for Topoisomerase 2 in Saccharomyces cerevisiae

  Relevance score: 0.00

  Gregory Tombline, Jonathan I. Millen, Bogdan Polevoda, Matan Rapaport, Bonnie Baxter, Michael Van Meter, Matthew Gilbertson, Joe Madrey, Gary A. Piazza, Lynn Rasmussen, Krister Wennerberg, E. Lucile White, John L. Nitiss, David S. Goldfarb

  Keywords: replicative lifespan, aging, topoisomerase 2 poison, DNA damage, antagonistic pleiotropy

  Published in Aging on January 5, 2017

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• PreviewVolume 1, Issue 11pp 884-886

  It's all about balance: p53 and aging

  Relevance score: 0.00

  Benoit Biteau, Heinrich Jasper

  Keywords: p53, aging, Drosophila, sexual dimorphism, antagonistic pleiotropy

  Published in Aging on November 13, 2009

• Research PaperVolume 12, Issue 24pp 25700-25717

  Inhibition of PAR-1 delays aging via activating AMPK in C. elegans

  Relevance score: 0.00

  Di Wu, Waijiao Cai, Xuan Zhang, Jianfeng Lan, Lina Zou, Samuel J. Chen, Zixing Wu, Di Chen

  Keywords: longevity, healthspan, PAR-1, AMPK, Caenorhabditis elegans

  Published in Aging on November 20, 2020

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• Research PaperVolume 3, Issue 12pp 1202-1205

  Exceptional longevity is associated with decreased reproduction

  Relevance score: 0.00

  Vafa Tabatabaie, Gil Atzmon, Swapnil N. Rajpathak, Ruth Freeman, Nir Barzilai, Jill Crandall

  Keywords: longevity, fertility, centenarian, reproduction, pregnancy, aging

  Published in Aging on December 26, 2011

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• ReviewVolume 17, Issue 12pp 2989-3002

  Aging as a multifactorial disorder with two stages

  Relevance score: 0.00

  David Gems, Alexander Carver, Yuan Zhao

  Keywords: aging, C. elegans, disease, hyperfunction, multifactorial model

  Published in Aging on December 30, 2025

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• Research PaperVolume 10, Issue 4pp 674-688

  Involvement of SPATA31 copy number variable genes in human lifespan

  Relevance score: 0.00

  Cemalettin Bekpen, Chen Xie, Almut Nebel, Diethard Tautz

  Keywords: SPATA31, primary foreskin fibroblast, senescence, human lifespan

  Published in Aging on April 19, 2018

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• ReviewVolume 6, Issue 2pp 84-91

  Evolution of sexually dimorphic longevity in humans

  Relevance score: 0.00

  David Gems

  Keywords: aging, eunuch, evolution, gender gap, menopause, polygyny, testosterone

  Published in Aging on February 22, 2014

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• Research PaperVolume 10, Issue 3pp 492-514

  Strong impact of natural-selection–free heterogeneity in genetics of age-related phenotypes

  Relevance score: 0.00

  Alexander M. Kulminski, Jian Huang, Yury Loika, Konstantin G. Arbeev, Olivia Bagley, Arseniy Yashkin, Matt Duan, Irina Culminskaya

  Keywords: genome-wide association studies, pleiotropy, age-related phenotypes, antagonistic genetic heterogeneity, aging, health span, life span

  Published in Aging on March 29, 2018

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• PreviewVolume 1, Issue 11pp 881-883

  p53, sex, and aging: lessons from the fruit fly

  Relevance score: 0.00

  Jae H. Hur, David W. Walker

  Keywords: Drosophila melanogaster, sexual antagonistic pleoitropy, longevity

  Published in Aging on November 13, 2009

• Research PaperVolume 1, Issue 4pp 412-424

  Dual targeting of the antagonistic pathways mediated by Sirt1 and TXNIP as a putative approach to enhance the efficacy of anti-aging interventions

  Relevance score: 0.00

  Shaker A. Mousa, Christine Gallati, Tessa Simone, Emmy Dier, Murat Yalcin, Evgeny Dyskin, Sudha Thangirala, Christine Hanko, Abdelhadi Rebbaa

  Keywords: Sirt1, TXNIP, DHEA, oxidative stress, metabolism, aging, stem cells

  Published in Aging on March 31, 2009

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• Research PaperVolume 13, Issue 9pp 13211-13224

  Circular RNA Plek promotes fibrogenic activation by regulating the miR-135b-5p/TGF-βR1 axis after spinal cord injury

  Relevance score: 0.00

  Wenzhao Wang, Dong He, Jianan Chen, Zhengdong Zhang, Shaoyi Wang, Yunpeng Jiang, Jianlu Wei

  Keywords: spinal cord injury, circular RNA, fibroblast, miR-135b-5p

  Published in Aging on May 11, 2021

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• Research PaperVolume 13, Issue 2pp 2436-2458

  FX5 as a non-steroidal GR antagonist improved glucose homeostasis in type 2 diabetic mice via GR/HNF4α/miR-122-5p pathway

  Relevance score: 0.00

  Xin Xu, Yidi Chen, Danyang Zhu, Tong Zhao, Rui Xu, Jiaying Wang, Lihong Hu, Xu Shen

  Keywords: type 2 diabetes, glucocorticoid receptor, gluconeogenesis, HNF4α, miR-122-5p

  Published in Aging on December 9, 2020

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• Research PaperVolume 9, Issue 12pp 2587-2609

  Mitogen-activated protein kinases, Fus3 and Kss1, regulate chronological lifespan in yeast

  Relevance score: 0.00

  Maneesha Aluru, Tori McKinney, Anne-Kathryn L. Venero, Shilpa Choudhury, Matthew Torres

  Keywords: MAPK, CLS, Tor1, Fus3, gene network

  Published in Aging on December 21, 2017

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• Research PaperVolume 16, Issue 7pp 6588-6612

  TGF-β downstream of Smad3 and MAPK signaling antagonistically regulate the viability and partial epithelial–mesenchymal transition of liver progenitor cells

  Relevance score: 0.00

  Yi-Min Sun, Yu Wu, Gan-Xun Li, Hui-Fang Liang, Tu-Ying Yong, Zifu Li, Bixiang Zhang, Xiao-Ping Chen, Guan-Nan Jin, Ze-Yang Ding

  Keywords: liver progenitor cells, proliferation, partial epithelial–mesenchymal transition, TGF-β, Smad3, MAPK signaling

  Published in Aging on April 5, 2024

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• Research PaperVolume 12, Issue 11pp 10642-10662

  Epigenome-wide gene–age interaction analysis reveals reversed effects of PRODH DNA methylation on survival between young and elderly early-stage NSCLC patients

  Relevance score: 0.00

  Chao Chen, Yongyue Wei, Liangmin Wei, Jiajin Chen, Xin Chen, Xuesi Dong, Jieyu He, Lijuan Lin, Ying Zhu, Hui Huang, Dongfang You, Linjing Lai, Sipeng Shen, Weiwei Duan, Li Su, Andrea Shafer, Thomas Fleischer, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Rui Wang, Johan Staaf, Åslaug Helland, Manel Esteller, Ruyang Zhang, Feng Chen, David C. Christiani

  Keywords: overall survival, DNA methylation, methylation–age interaction analysis, non-small cell lung cancer, aging

  Published in Aging on June 8, 2020

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