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• Priority Research PaperVolume 13, Issue 12pp 15750-15769

  Acid ceramidase promotes senescent cell survival

  Relevance score: 0.00

  Rachel Munk, Carlos Anerillas, Martina Rossi, Dimitrios Tsitsipatis, Jennifer L. Martindale, Allison B. Herman, Jen-Hao Yang, Jackson A. Roberts, Vijay R. Varma, Poonam R. Pandey, Madhav Thambisetty, Myriam Gorospe, Kotb Abdelmohsen

  Keywords: senotherapy, post-transcriptional, SASP, senescent cell metabolism, translational control

  Published in Aging on June 8, 2021

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• Research PaperVolume 6, Issue 7pp 575-586

  Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice

  Relevance score: 0.00

  Michael B. Stout, Tamara Tchkonia, Tamar Pirtskhalava, Allyson K. Palmer, Edward O. List, Darlene E. Berryman, Ellen R. Lubbers, Carlos Escande, Adam Spong, Michal M. Masternak, Ann L. Oberg, Nathan K. LeBrasseur, Richard A. Miller, John J. Kopchick, Andrzej Bartke, James L. Kirkland

  Keywords: adipose tissue, aging, cellular senescence, growth hormone

  Published in Aging on July 20, 2014

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• ReviewVolume 11, Issue 21pp 9947-9959

  Aging and stress induced β cell senescence and its implication in diabetes development

  Relevance score: 0.00

  Na Li, Furong Liu, Ping Yang, Fei Xiong, Qilin Yu, Jinxiu Li, Zhiguang Zhou, Shu Zhang, Cong-Yi Wang

  Keywords: senescence, β cell, β cell regeneration, insulin secretion, diabetes

  Published in Aging on November 13, 2019

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• Research PaperVolume 13, Issue 1pp 1294-1313

  Exercise reduces metabolic burden while altering the immune system in aged mice

  Relevance score: 0.00

  Kyeong Jin Yoon, Aram Ahn, Soo Hong Park, Seung Hee Kwak, Seong Eun Kwak, Wonsang Lee, Yong Ryoul Yang, Minji Kim, Hyun Mu Shin, Hang-Rae Kim, Hyo Youl Moon

  Keywords: exercise, immunosenescence, NK cell, aging, metabolism

  Published in Aging on January 6, 2021

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• Research PaperVolume 12, Issue 20pp 20001-20023

  Systemic overexpression of C-C motif chemokine ligand 2 promotes metabolic dysregulation and premature death in mice with accelerated aging

  Relevance score: 0.00

  Fedra Luciano-Mateo, Noemí Cabré, Gerard Baiges-Gaya, Salvador Fernández-Arroyo, Anna Hernández-Aguilera, Elisabet Elisabet Rodríguez-Tomàs, Meritxell Arenas, Jordi Camps, Javier A. Menéndez, Jorge Joven

  Keywords: C-C motif chemokine ligand 2, energy metabolism, one-carbon metabolism, progeria

  Published in Aging on October 26, 2020

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• Research PaperVolume 12, Issue 14pp 13958-13978

  Decreased autophagy and fuel switching occur in a senescent hepatic cell model system

  Relevance score: 0.00

  Brijesh Kumar Singh, Madhulika Tripathi, Reddemma Sandireddy, Keziah Tikno, Jin Zhou, Paul Michael Yen

  Keywords: aging, liver, senescence, metabolism, AML12 cells

  Published in Aging on July 26, 2020

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• Research PerspectiveVolume 11, Issue 3pp 1065-1068

  Hallmarks of the cancer cell of origin: Comparisons with “energetic” cancer stem cells (e-CSCs)

  Relevance score: 0.00

  Federica Sotgia, Marco Fiorillo, Michael P. Lisanti

  Keywords: cancer cell of origin, cancer stem cells (CSCs), senescence, metabolism, anti-oxidant response, tamoxifen resistance

  Published in Aging on February 13, 2019

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• Research PaperVolume 10, Issue 3pp 434-462

  Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence

  Relevance score: 0.00

  Blanka Mrazkova, Rastislav Dzijak, Terezie Imrichova, Lenka Kyjacova, Peter Barath, Petr Dzubak, Dusan Holub, Marian Hajduch, Zuzana Nahacka, Ladislav Andera, Petr Holicek, Pavla Vasicova, Olena Sapega, Jiri Bartek, Zdenek Hodny

  Keywords: mass spectrometry, SILAC, proteomics, MAPK pathway, aging

  Published in Aging on March 28, 2018

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• Research PaperVolume 8, Issue 12pp 3375-3389

  Impaired energy metabolism of senescent muscle satellite cells is associated with oxidative modifications of glycolytic enzymes

  Relevance score: 0.00

  Martín A. Baraibar, Janek Hyzewicz, Adelina Rogowska-Wrzesinska, Anne-Laure Bulteau, Carina Prip-Buus, Gillian Butler-Browne, Bertrand Friguet

  Keywords: protein oxidation, proteostasis, myoblasts, aging, cellular senescence, energy metabolism

  Published in Aging on December 4, 2016

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• Research PaperVolume 11, Issue 11pp 3505-3522

  Nicotinamide phosphoribosyltransferase postpones rat bone marrow mesenchymal stem cell senescence by mediating NAD⁺–Sirt1 signaling

  Relevance score: 0.00

  Chenchen Pi, Yue Yang, Yanan Sun, Huan Wang, Hui Sun, Mao Ma, Lin Lin, Yingai Shi, Yan Li, Yulin Li, Xu He

  Keywords: Nampt, mesenchymal stem cells (MSC), senescence, NAD ⁺, Sirt1, regenerative medicine

  Published in Aging on June 7, 2019

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• Research PaperVolume 3, Issue 11pp 1078-1091

  Yeast-like chronological senescence in mammalian cells: phenomenon, mechanism and pharmacological suppression

  Relevance score: 0.00

  Olga V. Leontieva, Mikhail V. Blagosklonny

  Keywords: chronological aging, senescence, metabolism, rapamycin, mTOR, lactate

  Published in Aging on December 10, 2011

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• Research PaperVolume 10, Issue 6pp 1239-1256

  Mitochondrial peptides modulate mitochondrial function during cellular senescence

  Relevance score: 0.00

  Su-Jeong Kim, Hemal H. Mehta, Junxiang Wan, Chisaka Kuehnemann, Jingcheng Chen, Ji-Fan Hu, Andrew R. Hoffman, Pinchas Cohen

  Keywords: mitochondria, senescence, mitochondrial-derived peptides, mitochondrial energetics, mtDNA methylation, SASP (senescence-associated secretory phenotype)

  Published in Aging on June 10, 2018

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• ReviewVolume 18, Issue 1pp 421-454

  Cellular senescence: from pathogenic mechanisms to precision anti-aging interventions

  Relevance score: 0.00

  Jian Deng, Ruipu Sun, Zhiyong Bai, Lisha Fang, Xudong Zhao, Dong Yang

  Keywords: cellular senescence, aging mechanisms, functional heterogeneity, precision anti-aging

  Published in Aging on May 4, 2026

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• Research PaperVolume 12, Issue 9pp 8241-8260

  Long-noncoding RNA MALAT1 sponges microRNA-92a-3p to inhibit doxorubicin-induced cardiac senescence by targeting ATG4a

  Relevance score: 0.00

  Wenzheng Xia, Hanbin Chen, Congying Xie, Meng Hou

  Keywords: exosome derived from mesenchymal stem cells, hypoxia, doxorubicin related cardiac senescence, LncRNA-MALAT1/miR-92a-3p/ATG4a signaling pathway, mitochondrial metabolism

  Published in Aging on May 8, 2020

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• Research PaperVolume 17, Issue 2pp 365-392

  Mitochondrial dysfunction, iron accumulation, lipid peroxidation, and inflammasome activation in cellular models derived from patients with multiple sclerosis

  Relevance score: 0.00

  Raquel García-Salas, Paula Cilleros-Holgado, Anna Di Spirito, David Gómez-Fernández, Rocío Piñero-Pérez, José Manuel Romero-Domínguez, Mónica Álvarez-Córdoba, Diana Reche-López, Ana Romero-González, Alejandra López-Cabrera, José Antonio Sánchez-Alcázar

  Keywords: multiple sclerosis, iron accumulation, lipid peroxidation, inflammasome, mitochondrial dysfunction

  Published in Aging on February 6, 2025

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• Research PaperVolume 8, Issue 10pp 2337-2354

  TGF-β and NF-κB signaling pathway crosstalk potentiates corneal epithelial senescence through an RNA stress response

  Relevance score: 0.00

  Zhi-Yuan Li, Zhao-Li Chen, Ting Zhang, Chao Wei, Wei-Yun Shi

  Keywords: corneal epithelium, cellular senescence, transforming growth factor-β, RNA stress granules, nuclear factor-κB

  Published in Aging on October 6, 2016

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• Research PaperVolume 12, Issue 7pp 6089-6108

  Estradiol-induced senescence of hypothalamic astrocytes contributes to aging-related reproductive function declines in female mice

  Relevance score: 0.00

  Xiaoman Dai, Luyan Hong, Hui Shen, Qiang Du, Qinyong Ye, Xiaochun Chen, Jing Zhang

  Keywords: estradiol, aging, hypothalamic astrocyte, reproduction, GnRH

  Published in Aging on April 7, 2020

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• Research PaperVolume 11, Issue 8pp 2202-2216

  Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs)

  Relevance score: 0.00

  Marco Fiorillo, Fanni Tóth, Federica Sotgia, Michael P. Lisanti

  Keywords: Doxycycline, Azithromycin, Vitamin C, combination therapy, mitochondrial ATP depletion, glycolysis

  Published in Aging on April 19, 2019

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• Research PaperVolume 9, Issue 10pp 2137-2162

  SOCS1 regulates senescence and ferroptosis by modulating the expression of p53 target genes

  Relevance score: 0.00

  Emmanuelle Saint-Germain, Lian Mignacca, Mathieu Vernier, Diwakar Bobbala, Subburaj Ilangumaran, Gerardo Ferbeyre

  Keywords: suppressor of cytokine signaling, tumor suppressor, ferroptosis, senescence, KAP1

  Published in Aging on October 28, 2017

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• Research PerspectiveVolume 11, Issue 16pp 6591-6601

  In silico clinical trials for anti-aging therapies

  Relevance score: 0.00

  Javier A. Menendez, Elisabet Cuyàs, Núria Folguera-Blasco, Sara Verdura, Begoña Martin-Castillo, Jorge Joven, Tomás Alarcón

  Keywords: aging, cancer, inflammation, senolytics, biomathematics

  Published in Aging on August 24, 2019

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