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  • Research PaperVolume 9, Issue 9pp 1983-1995

    Leukocyte telomere length, T cell composition and DNA methylation age

    Relevance score: 0.00

    Brian H. Chen, Cara L. Carty, Masayuki Kimura, Jeremy D. Kark, Wei Chen, Shengxu Li, Tao Zhang, Charles Kooperberg, Daniel Levy, Themistocles Assimes, Devin Absher, Steve Horvath, Alexander P. Reiner, Abraham Aviv

    Keywords: telomeres, aging, T cells, DNA methylation, memory, naïve

    Published in Aging on September 20, 2017

  • Priority Research PaperVolume 8, Issue 9pp 1844-1865

    DNA methylation-based measures of biological age: meta-analysis predicting time to death

    Relevance score: 0.00

    Brian H. Chen, Riccardo E. Marioni, Elena Colicino, Marjolein J. Peters, Cavin K. Ward-Caviness, Pei-Chien Tsai, Nicholas S. Roetker, Allan C. Just, Ellen W. Demerath, Weihua Guan, Jan Bressler, Myriam Fornage, Stephanie Studenski, Amy R. Vandiver, Ann Zenobia Moore, Toshiko Tanaka, Douglas P. Kiel, Liming Liang, Pantel Vokonas, Joel Schwartz, Kathryn L. Lunetta, Joanne M. Murabito, Stefania Bandinelli, Dena G. Hernandez, David Melzer, Michael Nalls, Luke C. Pilling, Timothy R. Price, Andrew B. Singleton, Christian Gieger, Rolf Holle, Anja Kretschmer, Florian Kronenberg, Sonja Kunze, Jakob Linseisen, Christine Meisinger, Wolfgang Rathmann, Melanie Waldenberger, Peter M. Visscher, Sonia Shah, Naomi R. Wray, Allan F. McRae, Oscar H. Franco, Albert Hofman, André G. Uitterlinden, Devin Absher, Themistocles Assimes, Morgan E. Levine, Ake T. Lu, Philip S. Tsao, Lifang Hou, JoAnn E. Manson, Cara L. Carty, Andrea Z. LaCroix, Alexander P. Reiner, Tim D. Spector, Andrew P. Feinberg, Daniel Levy, Andrea Baccarelli, Joyce van Meurs, Jordana T. Bell, Annette Peters, Ian J. Deary, James S. Pankow, Luigi Ferrucci, Steve Horvath

    Keywords: all-cause mortality, lifespan, epigenetics, epigenetic clock, DNA methylation, mortality

    Published in Aging on September 28, 2016

  • Research PaperVolume 10, Issue 4pp 573-591

    An epigenetic biomarker of aging for lifespan and healthspan

    Relevance score: 0.00

    Morgan E. Levine, Ake T. Lu, Austin Quach, Brian H. Chen, Themistocles L. Assimes, Stefania Bandinelli, Lifang Hou, Andrea A. Baccarelli, James D. Stewart, Yun Li, Eric A. Whitsel, James G Wilson, Alex P Reiner, Abraham Aviv, Kurt Lohman, Yongmei Liu, Luigi Ferrucci, Steve Horvath

    Keywords: epigenetic clock, DNA methylation, biomarker, healthspan

    Published in Aging on April 18, 2018

  • Research PaperVolume 9, Issue 2pp 419-446

    Epigenetic clock analysis of diet, exercise, education, and lifestyle factors

    Relevance score: 0.00

    Austin Quach, Morgan E. Levine, Toshiko Tanaka, Ake T. Lu, Brian H. Chen, Luigi Ferrucci, Beate Ritz, Stefania Bandinelli, Marian L. Neuhouser, Jeannette M. Beasley, Linda Snetselaar, Robert B. Wallace, Philip S. Tsao, Devin Absher, Themistocles L. Assimes, James D. Stewart, Yun Li, Lifang Hou, Andrea A. Baccarelli, Eric A. Whitsel, Steve Horvath

    Keywords: diet, lifestyle, fish intake, alcohol intake, aging, epigenetic clock, DNA methylation

    Published in Aging on February 14, 2017

  • Research PaperVolume 13, Issue 20pp 23471-23516

    Predicting physiological aging rates from a range of quantitative traits using machine learning

    Relevance score: 0.00

    Eric D. Sun, Yong Qian, Richard Oppong, Thomas J. Butler, Jesse Zhao, Brian H. Chen, Toshiko Tanaka, Jian Kang, Carlo Sidore, Francesco Cucca, Stefania Bandinelli, Gonçalo R. Abecasis, Myriam Gorospe, Luigi Ferrucci, David Schlessinger, Ilya Goldberg, Jun Ding

    Keywords: physiological aging rate, quantitative trait, machine learning, aging clock, mortality, personalized medicine

    Published in Aging on October 29, 2021

  • Meeting ReportVolume 14, Issue 2pp 530-543

    Meeting Report: Aging Research and Drug Discovery

    Relevance score: 0.00

    Esther Meron, Maria Thaysen, Suzanne Angeli, Adam Antebi, Nir Barzilai, Joseph A. Baur, Simon Bekker-Jensen, Maria Birkisdottir, Evelyne Bischof, Jens Bruening, Anne Brunet, Abigail Buchwalter, Filipe Cabreiro, Shiqing Cai, Brian H. Chen, Maria Ermolaeva, Collin Y. Ewald, Luigi Ferrucci, Maria Carolina Florian, Kristen Fortney, Adam Freund, Anastasia Georgievskaya, Vadim N. Gladyshev, David Glass, Tyler Golato, Vera Gorbunova, Jan Hoejimakers, Riekelt H. Houtkooper, Sibylle Jager, Frank Jaksch, Georges Janssens, Martin Borch Jensen, Matt Kaeberlein, Gerard Karsenty, Peter de Keizer, Brian Kennedy, James L. Kirkland, Michael Kjaer, Guido Kroemer, Kai-Fu Lee, Jean-Marc Lemaitre, David Liaskos, Valter D. Longo, Yu-Xuan Lu, Michael R. MacArthur, Andrea B. Maier, Christina Manakanatas, Sarah J. Mitchell, Alexey Moskalev, Laura Niedernhofer, Ivan Ozerov, Linda Partridge, Emmanuelle Passegué, Michael A. Petr, James Peyer, Dina Radenkovic, Thomas A. Rando, Suresh Rattan, Christian G. Riedel, Lenhard Rudolph, Ruixue Ai, Manuel Serrano, Björn Schumacher, David A. Sinclair, Ryan Smith, Yousin Suh, Pam Taub, Alexandre Trapp, Anne-Ulrike Trendelenburg, Dario Riccardo Valenzano, Kris Verburgh, Eric Verdin, Jan Vijg, Rudi G.J. Westendorp, Alessandra Zonari, Daniela Bakula, Alex Zhavoronkov, Morten Scheibye-Knudsen

    Keywords: aging, drug discovery, conference, AI, longevity

    Published in Aging on January 28, 2022

  • Research PaperVolume 15, Issue 10pp 3967-3983

    Vascular endothelial growth factor receptor 1 gene (FLT1) longevity variant increases lifespan by reducing mortality risk posed by hypertension

    Relevance score: 0.00

    Brian J. Morris, Randi Chen, Timothy A. Donlon, Kalpana J. Kallianpur, Kamal H. Masaki, Bradley J. Willcox

    Keywords: lifespan, genetics, hypertension, coronary heart disease, diabetes

    Published in Aging on May 12, 2023

  • Research PaperVolume 13, Issue 6pp 7953-7974

    Lifespan extension conferred by mitogen-activated protein kinase kinase kinase 5 (MAP3K5) longevity-associated gene variation is confined to at-risk men with a cardiometabolic disease

    Relevance score: 0.00

    Brian J. Morris, Randi Chen, Timothy A. Donlon, Kamal H. Masaki, D. Craig Willcox, Richard C. Allsopp, Bradley J. Willcox

    Keywords: lifespan, genetics, diabetes, hypertension, coronary heart disease

    Published in Aging on March 19, 2021

  • Research PaperVolume 12, Issue 23pp 23509-23524

    FOXO3 longevity genotype mitigates the increased mortality risk in men with a cardiometabolic disease

    Relevance score: 0.00

    Randi Chen, Brian J. Morris, Timothy A. Donlon, Kamal H. Masaki, D. Craig Willcox, Philip M.C. Davy, Richard C. Allsopp, Bradley J. Willcox

    Keywords: longevity, genetics, mortality, FOXO3, resilience

    Published in Aging on December 1, 2020

  • Research PaperVolume 13, Issue 11pp 14745-14767

    Association of growth hormone receptor gene variant with longevity in men is due to amelioration of increased mortality risk from hypertension

    Relevance score: 0.00

    Timothy A. Donlon, Randi Chen, Kamal H. Masaki, D. Craig Willcox, Richard C. Allsopp, Bradley J. Willcox, Brian J. Morris

    Keywords: hypertension, growth hormone receptor, longevity, mortality

    Published in Aging on June 1, 2021

  • Research PaperVolume 7, Issue 9pp 690-700

    DNA methylation age of blood predicts future onset of lung cancer in the women's health initiative

    Relevance score: 0.00

    Morgan E. Levine, H. Dean Hosgood, Brian Chen, Devin Absher, Themistocles Assimes, Steve Horvath

    Keywords: epigenetic clock, biological age, lung cancer

    Published in Aging on September 24, 2015

  • Research PaperVolume 7, Issue 11pp 911-927

    A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition

    Relevance score: 0.00

    Clemens Stockklausner, Simon Raffel, Julia Klermund, Obul Reddy Bandapalli, Fabian Beier, Tim H. Brümmendorf, Friederike Bürger, Sven W. Sauer, Georg F. Hoffmann, Holger Lorenz, Laura Tagliaferri, Daniel Nowak, Wolf-Karsten Hofmann, Rebecca Buergermeister, Carolin Kerber, Tobias Rausch, Jan O. Korbel, Brian Luke, Andreas Trumpp, Andreas E. Kulozik

    Keywords: TERT, TERC, mTOR, rapamycin, sirolimus, senescence

    Published in Aging on November 6, 2015

  • Meeting ReportVolume 18, Issue 1pp 282-302

    Toward actionable interventions in human aging (12th ARDD meeting, 2025)

    Relevance score: 0.00

    Aleksandr Dekan, Sierra Lore, Ye Eun Yoon, Aisyah Sjöholm, Alexander Tyshkovskiy, Alexey Terskikh, Ana Maria Cuervo, Anastasia Georgievskaya, Andrea Heinz, Andrei Seluanov, Andrew Adams, Andy P. Tsai, Anna Murray, Anne Brunet, Anne Marije van Harten, Avi Spier, Ben Shenhar, Bente Klarlund Pedersen, Berthil Clasen, Björn Schumacher, Brian K. Kennedy, Charlotte Suetta, Christiane Volbracht, Christoph Kuppe, Clive Cookson, Collin Y. Ewald, Cristiana Banila, Daisy Cai, Dario Riccardo Valenzano, Dudley W. Lamming, Edward Rudnic, Elias Bou Samra, Emma Teeling, Eric Verdin, Evandro Fei Fang, Fabrizio d’Adda di Fagagna, Fedor Galkin, Garri Zmudze, Heinrich Jasper, In Hwa Jang, Jing-Dong Jackie Han, Jamie Justice, Jan H. J. Hoeijmakers, Javier María Peralta Ramos, Jean-Marc Lemaitre, Jeroen Aerssens, Joe Betts-LaCroix, John C. Newman, Juan Carlos Izpisua Belmonte, Kazuto Kawamura, Kennedy Matsagas Schaal, Kitsu Egerton, Kotb Abdelmohsen, Kristen Fortney, Lars Hartenstein, Laura Niedernhofer, Lida Katsimpardi, Lisa Melton, Lotte Bjerre Knudsen, Luigi Ferrucci, Lykke Sylow, Marco Demaria, Marissa J. Schafer, Marta Guasch-Ferré, Martin Borch-Jensen, Maxim Kholin, Michael Antonov, Michael Levitt, Michela Deleidi, Miriam Merad, Morten Meldal, Mourad Topors, Murali Venkatesan, Nathan K. LeBrasseur, Niklas Anzinger, Peter Fedichev, Paul Kohlhaas, Peter J. Mullen, Priya Singhal, Rafael de Cabo, Riekelt H. Houtkooper, Rusty Montgomery, Ryan Smith, Sharon Rosenzweig-Lipson, Sergey Jakimov, Steve Horvath, Steven Austad, Thomas A. Rando, Todd White, Tom Zuber, Tomaz Rozmaric, Tony Wyss-Coray, Tuomas Tammela, Vadim N. Gladyshev, Vanessa V. C. Sinatti, Weilan Wang, William Harborne, Xiaodong Liu, Xing Li Wang, Yousin Suh, Yuta Lee, Zane Koch, Alex Zhavoronkov, Morten Scheibye-Knudsen, Daniela Bakula

    Keywords: aging, longevity, geroscience, biomarkers, rejuvenation

    Published in Aging on April 6, 2026

  • Meeting ReportVolume 12, Issue 24pp 24484-24503

    ARDD 2020: from aging mechanisms to interventions

    Relevance score: 0.00

    Garik V. Mkrtchyan, Kotb Abdelmohsen, Pénélope Andreux, Ieva Bagdonaite, Nir Barzilai, Søren Brunak, Filipe Cabreiro, Rafael de Cabo, Judith Campisi, Ana Maria Cuervo, Marco Demaria, Collin Y. Ewald, Evandro Fei Fang, Richard Faragher, Luigi Ferrucci, Adam Freund, Carlos G. Silva-García, Anastasia Georgievskaya, Vadim N. Gladyshev, David J. Glass, Vera Gorbunova, Aubrey de Grey, Wei-Wu He, Jan Hoeijmakers, Eva Hoffmann, Steve Horvath, Riekelt H. Houtkooper, Majken K. Jensen, Martin Borch Jensen, Alice Kane, Moustapha Kassem, Peter de Keizer, Brian Kennedy, Gerard Karsenty, Dudley W. Lamming, Kai-Fu Lee, Nanna MacAulay, Polina Mamoshina, Jim Mellon, Marte Molenaars, Alexey Moskalev, Andreas Mund, Laura Niedernhofer, Brenna Osborne, Heidi H. Pak, Andrey Parkhitko, Nuno Raimundo, Thomas A. Rando, Lene Juel Rasmussen, Carolina Reis, Christian G. Riedel, Anais Franco-Romero, Björn Schumacher, David A. Sinclair, Yousin Suh, Pam R. Taub, Debra Toiber, Jonas T. Treebak, Dario Riccardo Valenzano, Eric Verdin, Jan Vijg, Sergey Young, Lei Zhang, Daniela Bakula, Alex Zhavoronkov, Morten Scheibye-Knudsen

    Keywords: aging, interventions, drug discovery, artificial intelligence

    Published in Aging on December 30, 2020

  • Research PaperVolume 8, Issue 10pp 2590-2602

    Haploinsufficiency of the Myc regulator Mtbp extends survival and delays tumor development in aging mice

    Relevance score: 0.00

    Brian C. Grieb, Kelli Boyd, Ramkrishna Mitra, Christine M. Eischen

    Keywords: Mtbp, Myc, aging, longevity, lymphoma

    Published in Aging on October 30, 2016

  • Research PaperVolume 12, Issue 10pp 9686-9713

    Ovulation and ovarian wound healing are impaired with advanced reproductive age

    Relevance score: 0.00

    Jamie N. Mara, Luhan T. Zhou, Megan Larmore, Brian Johnson, Rebecca Ayiku, Farners Amargant, Michele T. Pritchard, Francesca E. Duncan

    Keywords: ovulation, fibrosis, wound healing, ovary, reproductive aging

    Published in Aging on May 14, 2020

  • Research PaperVolume 3, Issue 6pp 621-634

    Store-Operated Ca2+ Entry (SOCE) Contributes to Normal Skeletal Muscle Contractility in young but not in aged skeletal muscle

    Relevance score: 0.00

    Angela M Thornton, Xiaoli Zhao, Noah Weisleder, Leticia S. Brotto, Sylvain Bougoin, Thomas M. Nosek, Michael Reid, Brian Hardin, Zui Pan, Jianjie Ma, Jerome Parness, Marco Brotto

    Keywords: SOCE, calcium entry, muscle contraction, muscle aging, aging

    Published in Aging on June 6, 2011

  • Meeting ReportVolume 9, Issue 4pp 1090-1095

    2nd interventions in aging conference

    Relevance score: 0.00

    Brian K. Kennedy, Linda Partridge

    Keywords: healthspan, organismal aging, epigenetics, longevity, cellular mechanisms, metabolism

    Published in Aging on April 27, 2017

  • Research PaperVolume 8, Issue 11pp 2988-3008

    Transgenerational programming of longevity through E(z)-mediated histone H3K27 trimethylation in Drosophila

    Relevance score: 0.00

    Brian Xia, Ed Gerstin, Dustin E. Schones, Wendong Huang, J. Steven de Belle

    Keywords: transgenerational inheritance, nutritional programming, longevity, H3K27me3, E(z)

    Published in Aging on November 25, 2016

  • Research PaperVolume 8, Issue 5pp 1115-1134

    Transgenerational programming of longevity and reproduction by post-eclosion dietary manipulation in Drosophila

    Relevance score: 0.00

    Brian Xia, Steven de Belle

    Published in Aging on March 28, 2016