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• Research PaperVolume 9, Issue 8pp 1867-1884

  p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli

  Relevance score: 0.00

  Brandon M. Hall, Vitaly Balan, Anatoli S. Gleiberman, Evguenia Strom, Peter Krasnov, Lauren P. Virtuoso, Elena Rydkina, Slavoljub Vujcic, Karina Balan, Ilya I. Gitlin, Katerina I. Leonova, Camila R. Consiglio, Sandra O. Gollnick, Olga B. Chernova, Andrei V. Gudkov

  Keywords: aging, macrophage, senescent cell, p16(Ink4a), beta-galactosidase

  Published in Aging on August 2, 2017

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• Research PaperVolume 8, Issue 7pp 1294-1315

  Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells

  Relevance score: 0.00

  Brandon M. Hall, Vitaly Balan, Anatoli S. Gleiberman, Evguenia Strom, Peter Krasnov, Lauren P. Virtuoso, Elena Rydkina, Slavoljub Vujcic, Karina Balan, Ilya Gitlin, Katerina Leonova, Alexander Polinsky, Olga B. Chernova, Andrei V. Gudkov

  Keywords: chronological aging, inflammation, inflammaging, senescence-associated beta-galactosidase, p16INK4a, senescence-associated secretory phenotype, clodronate

  Published in Aging on July 6, 2016

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• Research PaperVolume 3, Issue 12pp 1192-1201

  Robust nuclear lamina-based cell classification of aging and senescent cells

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  Christiaan H. Righolt, Merel L.R. van 't Hoff, Bart J. Vermolen, Ian T. Young, Vered Raz

  Keywords: cell senescence, aging cells, apoptosis, nuclear lamina, image processing

  Published in Aging on December 24, 2011

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• EditorialVolume 5, Issue 8pp 590-591

  p16INK4a in cellular senescence

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  Elisabeth Simboeck, Luciano Di Croce

  Published in Aging on August 17, 2013

• Research PaperVolume 15, Issue 2pp 441-458

  Clearance of p16Ink4a-positive cells in a mouse transgenic model does not change β-cell mass and has limited effects on their proliferative capacity

  Relevance score: 0.00

  Nadine Bahour, Lucia Bleichmar, Cristian Abarca, Emeline Wilmann, Stephanie Sanjines, Cristina Aguayo-Mazzucato

  Keywords: beta cells, mass, proliferation, senolysis, senescence

  Published in Aging on January 12, 2023

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• Research PerspectiveVolume 1, Issue 11pp 949-953

  Paradoxical down-regulation of p16^INK4a mRNA with advancing age in Acute Myeloid Leukemia

  Relevance score: 0.00

  Hendrik J.M. de Jonge, Carolien M. Woolthuis, Eveline S.J.M. de Bont, Gerwin Huls

  Keywords: p16INK4a, aging, Acute Myeloid Leukemia, senescence

  Published in Aging on October 23, 2009

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• Research PaperVolume 9, Issue 2pp 494-507

  CDKN2A/p16INK4^a expression is associated with vascular progeria in chronic kidney disease

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  Peter Stenvinkel, Karin Luttropp, Dagmara McGuinness, Anna Witasp, Abdul Rashid Qureshi, Annika Wernerson, Louise Nordfors, Martin Schalling, Jonaz Ripsweden, Lars Wennberg, Magnus Söderberg, Peter Bárány, Hannes Olauson, Paul G Shiels

  Keywords: chronic kidney disease, vascular calcification, vascular senescence, vitamin, p16

  Published in Aging on February 9, 2017

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• Research PaperVolume 12, Issue 20pp 20226-20234

  Aerobic exercise induces tumor suppressor p16^INK4a expression of endothelial progenitor cells in human skeletal muscle

  Relevance score: 0.00

  Jinfu Wu, I-Shiung Cheng, Suchada Saovieng, Wei-Horng Jean, Chung-Lan Kao, Yung-Yang Liu, Chih-Yang Huang, Tania Xu Yar Lee, John L. Ivy, Chia-Hua Kuo

  Keywords: cancer, tumor, cell cycle arrest, skeletal muscle

  Published in Aging on October 26, 2020

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• Research PaperVolume 16, Issue 13pp 10749-10764

  Cathepsin L induces cellular senescence by upregulating CUX1 and p16^INK4a

  Relevance score: 0.00

  Yuwei Wu, Danli Jiang, Qing Liu, Shaoyang Yan, Xiuzhen Liu, Ting Wu, Wei Sun, Gang Li

  Keywords: senescence, atherosclerosis, p16^INK4a, Cathepsin L, CUX1

  Published in Aging on June 18, 2024

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• Research PaperVolume 16, Issue 21pp 13225-13236

  Adolescents and young adults with sickle cell disease exhibit accelerated aging with elevated T-cell p16^INK4a expression

  Relevance score: 0.00

  Samuel R. Wilson, Natalia Mitin, Vanessa L. Ayer Miller, Andrew B. Smitherman, Marcus A. Carden

  Keywords: sickle cell disease, aging, p16, adolescents, young adults

  Published in Aging on November 14, 2024

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• Research PaperVolume 5, Issue 2pp 120-129

  How to measure RNA expression in rare senescent cells expressing any specific protein such as p16^Ink4a

  Relevance score: 0.00

  Jessie C. Jeyapalan, John M. Sedivy

  Keywords: Cellular senescence, flow cytometry, immunostaining, RNA purification, transcriptome profiling

  Published in Aging on February 25, 2013

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• Research PaperVolume 12, Issue 16pp 16476-16490

  Relationship closeness buffers the effects of perceived stress on transcriptomic indicators of cellular stress and biological aging marker p16^INK4a

  Relevance score: 0.00

  Kelly E. Rentscher, Judith E. Carroll, Steve W. Cole, Rena L. Repetti, Theodore F. Robles

  Keywords: psychological stress, relationship closeness, biological aging, cellular senescence, gene expression

  Published in Aging on July 26, 2020

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• Research PaperVolume 12, Issue 8pp 6700-6732

  Mitochondrial nucleoid remodeling and biogenesis are regulated by the p53-p21^WAF1-PKCζ pathway in p16^INK4a-silenced cells

  Relevance score: 0.00

  Yun Yeong Lee, Yeon Seung Choi, Do Wan Kim, Jae Youn Cheong, Kye Yong Song, Min Sook Ryu, In Kyoung Lim

  Keywords: senescence, p53-p21-PKCζ activation, p16INK4a silence, mitochondria, nucleoid remodeling

  Published in Aging on April 24, 2020

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• Research PaperVolume 6, Issue 3pp 160-175

  MicroRNA-29 induces cellular senescence in aging muscle through multiple signaling pathways

  Relevance score: 0.00

  Zhaoyong Hu, Janet D. Klein, William E. Mitch, Liping Zhang, Ivan Martinez, Xiaonan H. Wang

  Keywords: p50, p16Ink4A, RB, B-myb, sarcopenia, p85, IGF-1

  Published in Aging on March 12, 2014

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• Research PaperVolume 10, Issue 6pp 1356-1365

  Aged cells in human skeletal muscle after resistance exercise

  Relevance score: 0.00

  Chi Yang, Ying Jiao, Bing Wei, Zeyi Yang, Jin-Fu Wu, Jorgen Jensen, Wei-Horng Jean, Chih-Yang Huang, Chia-Hua Kuo

  Keywords: anti-aging, inflammation, p16Ink4a, macrophage, whey protein

  Published in Aging on June 27, 2018

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• Research PaperVolume 15, Issue 3pp 765-776

  Senolytic effect of high intensity interval exercise on human skeletal muscle

  Relevance score: 0.00

  Wei-Horng Jean, Yu-Wen Hsieh, Li-Fan Lai, Luthfia Dewi, Yu-Chieh Liao, Mengxin Ye, Szu-Hsien Yu, Chung-Lan Kao, Chih-Yang Huang, Chia-Hua Kuo

  Keywords: DNA repair, inflammation, p16^Ink4a, γ-H2AX, CD11b, HIIT, cycling

  Published in Aging on February 8, 2023

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• Research PaperVolume 11, Issue 20pp 9128-9146

  Mesenchymal stem cell senescence alleviates their intrinsic and seno-suppressive paracrine properties contributing to osteoarthritis development

  Relevance score: 0.00

  Olivier Malaise, Yassin Tachikart, Michael Constantinides, Marcus Mumme, Rosanna Ferreira-Lopez, Sandra Noack, Christian Krettek, Daniele Noël, Jing Wang, Christian Jorgensen, Jean-Marc Brondello

  Keywords: senescence, tissue homeostasis, osteoarthritis, mesenchymal stem cell

  Published in Aging on October 22, 2019

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• Research PaperVolume 13, Issue 12pp 16567-16576

  Reduced stem cell aging in exercised human skeletal muscle is enhanced by ginsenoside Rg1

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  Tania Xu Yar Lee, Jinfu Wu, Wei-Horng Jean, Giancarlo Condello, Ahmad Alkhatib, Chao-Chieh Hsieh, Yu-Wen Hsieh, Chih-Yang Huang, Chia-Hua Kuo

  Keywords: p16^INK4a, resistance exercise, Rg1, senolytic, cellular senescence, CD4

  Published in Aging on June 28, 2021

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• Priority Research PaperVolume 13, Issue 10pp 13380-13392

  Cdkn1a transcript variant 2 is a marker of aging and cellular senescence

  Relevance score: 0.00

  José Alberto López-Domínguez, Sandra Rodríguez-López, Ulises Ahumada-Castro, Pierre-Yves Desprez, Maria Konovalenko, Remi-Martin Laberge, César Cárdenas, José Manuel Villalba, Judith Campisi

  Keywords: p21, p53, mouse dermal fibroblast, ionizing radiation, doxorubicin

  Published in Aging on May 25, 2021

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• Research PaperVolume 16, Issue 10pp 8599-8610

  Senolytic effects of exercise in human muscles require acute inflammation

  Relevance score: 0.00

  Wei-Horng Jean, Yin-Chou Lin, Pei-Yao Ang, Kazushige Goto, Chao-An Lin, Luthfia Dewi, Yu-Chieh Liao, Chih-Yang Huang, Chia-Hua Kuo

  Keywords: p16^INK4a, high-intensity intermittent exercise, cellular senescence, inflammation, NSAID

  Published in Aging on May 15, 2024

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