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• Research PaperVolume 18, Issue 1pp 67-81

  P38 MAPK is involved in epigenetic regulation of fibrotic genes in replication induced senescence in lung fibroblasts

  Relevance score: 0.00

  Shan Zhu, Jennifer Q Zhou, Kan Wang, Ming-lei Guo, Yan Y Sanders

  Keywords: senescence, fibroblast activation, p38 MAPK, lung fibrosis, H4K16Ac

  Published in Aging on March 3, 2026

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• Research PaperVolume 17, Issue 8pp 2113-2125

  DNMT1-mediated SPINT2 expression drives early senescence by suppressing c-Met signaling in human fibroblasts

  Relevance score: 0.00

  Min Seok Sim, Hae-Ok Byun, Seongki Min, Jiwon Hong, Su Bin Lim, Kyoung Sook Choi, Gyesoon Yoon

  Keywords: senescence, cellular senescence, aging, DNA methyltransferase 1 (DNMT1), serine protease inhibitor Kunitz type 2 (SPINT2)

  Published in Aging on August 20, 2025

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• Research PaperVolume 17, Issue 6pp 1452-1465

  Senescence caused by telomerase inactivation in myeloid, mesenchymal, and endothelial cells has distinct effects on cancer progression

  Relevance score: 0.00

  Joseph Rupert, Zhanguo Gao, Yongmei Yu, Mikhail G. Kolonin

  Keywords: senescence, telomerase, myeloid, mesenchymal, endothelial

  Published in Aging on June 5, 2025

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• Research PaperVolume 16, Issue 13pp 10670-10693

  Roles of pigment epithelium-derived factor in exercise-induced suppression of senescence and its impact on lung pathology in mice

  Relevance score: 0.00

  Hiromichi Tsushima, Hirobumi Tada, Azusa Asai, Mikako Hirose, Tohru Hosoyama, Atsushi Watanabe, Taro Murakami, Masataka Sugimoto

  Keywords: senescence, exercise, PEDF, myokine, COPD

  Published in Aging on June 26, 2024

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• Research PaperVolume 16, Issue 13pp 10749-10764

  Cathepsin L induces cellular senescence by upregulating CUX1 and p16^INK4a

  Relevance score: 0.00

  Yuwei Wu, Danli Jiang, Qing Liu, Shaoyang Yan, Xiuzhen Liu, Ting Wu, Wei Sun, Gang Li

  Keywords: senescence, atherosclerosis, p16^INK4a, Cathepsin L, CUX1

  Published in Aging on June 18, 2024

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• Research PaperVolume 16, Issue 9pp 7511-7522

  Germicidal lamps using UV-C radiation may pose health safety issues: a biomolecular analysis of their effects on apoptosis and senescence

  Relevance score: 0.00

  Nicola Alessio, Alessia Ambrosino, Andrea Boggi, Domenico Aprile, Iole Pinto, Giovanni Galano, Umberto Galderisi, Giovanni Di Bernardo

  Keywords: senescence, apoptosis, UV light, public health

  Published in Aging on May 2, 2024

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• Research PaperVolume 16, Issue 9pp 7704-7732

  Immune cell senescence and exhaustion promote the occurrence of liver metastasis in colorectal cancer by regulating epithelial-mesenchymal transition

  Relevance score: 0.00

  Sen Lin, Lanyue Ma, Jiaxin Mo, Ruiqi Zhao, Jinghao Li, Mengjiao Yu, Mei Jiang, Lisheng Peng

  Keywords: senescence, exhaustion, colorectal cancer liver metastases, epithelium-mesenchymal transition, machine learning

  Published in Aging on April 26, 2024

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• Research PaperVolume 16, Issue 4pp 3068-3087

  Mapping the core senescence phenotype of primary human colon fibroblasts

  Relevance score: 0.00

  Namita Ganesh Hattangady, Kelly Carter, Brett Maroni-Rana, Ting Wang, Jessica Lee Ayers, Ming Yu, William M. Grady

  Keywords: senescence, senescence associated secretory phenotype, SASP, colorectal cancer, cancer

  Published in Aging on February 21, 2024

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• Research PaperVolume 16, Issue 4pp 3531-3553

  Senescence-related genes analysis in breast cancer reveals the immune microenvironment and implications for immunotherapy

  Relevance score: 0.00

  Hua Zhong, Lijie Chang, Shengbin Pei, Yakun Kang, Lili Yang, Yifan Wu, Nuo Chen, Yicheng Luo, Yixiao Zhou, Jiaheng Xie, Yiqin Xia

  Keywords: senescence, immune microenvironment, immunotherapy, risk signature, breast cancer

  Published in Aging on February 14, 2024

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• Research PaperVolume 16, Issue 3pp 2866-2886

  Comprehensive analysis of cellular senescence and immune microenvironment in papillary thyroid carcinoma

  Relevance score: 0.00

  Yinde Huang, Han Jiang, Guangwen Xu, Xin Li, Wenbin Chen, Yu Lun, Jian Zhang

  Keywords: papillary thyroid cancer, cellular senescence, aging, overall survival, TCGA

  Published in Aging on February 7, 2024

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• Research PaperVolume 15, Issue 24pp 14591-14606

  SRSF7 downregulation induces cellular senescence through generation of MDM2 variants

  Relevance score: 0.00

  Jiwon Hong, Seongki Min, Gyesoon Yoon, Su Bin Lim

  Keywords: senescence, cellular senescence, aging, alternative splicing, mouse double minute 2 homolog (MDM2)

  Published in Aging on December 29, 2023

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• Research PaperVolume 15, Issue 19pp 9948-9964

  Senescence-associated inflammation and inhibition of adipogenesis in subcutaneous fat in Werner syndrome

  Relevance score: 0.00

  Daisuke Sawada, Hisaya Kato, Hiyori Kaneko, Daisuke Kinoshita, Shinichiro Funayama, Takuya Minamizuka, Atsushi Takasaki, Katsushi Igarashi, Masaya Koshizaka, Aki Takada-Watanabe, Rito Nakamura, Kazuto Aono, Ayano Yamaguchi, Naoya Teramoto, Yukari Maeda, Tomohiro Ohno, Aiko Hayashi, Kana Ide, Shintaro Ide, Mayumi Shoji, Takumi Kitamoto, Yusuke Endo, Hideyuki Ogata, Yoshitaka Kubota, Nobuyuki Mitsukawa, Atsushi Iwama, Yasuo Ouchi, Naoya Takayama, Koji Eto, Katsunori Fujii, Tomozumi Takatani, Tadashi Shiohama, Hiromichi Hamada, Yoshiro Maezawa, Koutaro Yokote

  Keywords: Werner syndrome, premature aging, lipodystrophy, stromal vascular fraction, SASP

  Published in Aging on October 3, 2023

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• Research PaperVolume 15, Issue 17pp 8576-8593

  Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes

  Relevance score: 0.00

  Mélina Georget, Anaïs Defois, Romain Guiho, Nina Bon, Sophie Allain, Cécile Boyer, Boris Halgand, Denis Waast, Gaël Grimandi, Alban Fouasson-Chailloux, Jérôme Guicheux, Claire Vinatier

  Keywords: senescence, osteoarthritis, etoposide, IL-1β, chondrocytes

  Published in Aging on September 1, 2023

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• Research PaperVolume 15, Issue 15pp 7408-7423

  Senescence-related gene c-Myc affects bladder cancer cell senescence by interacting with HSP90B1 to regulate cisplatin sensitivity

  Relevance score: 0.00

  Yaxuan Wang, Haixia Zhu, Haifei Xu, Yifan Qiu, Yonghong Zhu, Xiaolin Wang

  Keywords: HSP90B1, c-Myc, prognosis, senescence, cisplatin

  Published in Aging on July 10, 2023

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• Research PaperVolume 15, Issue 11pp 4576-4599

  Senescence and senotherapies in biliary atresia and biliary cirrhosis

  Relevance score: 0.00

  Giulia Jannone, Eliano Bonaccorsi Riani, Catherine de Magnée, Roberto Tambucci, Jonathan Evraerts, Joachim Ravau, Pamela Baldin, Caroline Bouzin, Axelle Loriot, Laurent Gatto, Anabelle Decottignies, Mustapha Najimi, Etienne Marc Sokal

  Keywords: senescence, senotherapy, liver, biliary cirrhosis, biliary atresia

  Published in Aging on May 18, 2023

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• Research PaperVolume 15, Issue 9pp 3331-3355

  In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers

  Relevance score: 0.00

  Parinya Samakkarnthai, Dominik Saul, Lei Zhang, Zaira Aversa, Madison L. Doolittle, Jad G. Sfeir, Japneet Kaur, Elizabeth J. Atkinson, James R. Edwards, Graham G. Russell, Robert J. Pignolo, James L. Kirkland, Tamar Tchkonia, Laura J. Niedernhofer, David G. Monroe, Nathan K. Lebrasseur, Joshua N. Farr, Paul D. Robbins, Sundeep Khosla

  Keywords: senescence, senolytics, aging, bone, bisphosphonates

  Published in Aging on May 7, 2023

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• EditorialVolume 15, Issue 5pp 1232-1234

  Senescence and extracellular vesicles: novel partners in vascular amyloidosis

  Relevance score: 0.00

  Meredith Whitehead, Marco Antonazzi, Catherine M. Shanahan

  Keywords: amyloid, smooth muscle cells, senescence, extracellular vesicles, medin

  Published in Aging on March 1, 2023

• Research PaperVolume 15, Issue 5pp 1237-1256

  Senescence-associated exosomes transfer miRNA-induced fibrosis to neighboring cells

  Relevance score: 0.00

  Amy H. Lee, Deepraj Ghosh, Ivy L. Koh, Michelle R. Dawson

  Keywords: radiation-induced senescence, exosomes (EXOs), microRNA (miRNA), transforming growth factor-β (TGF-β), mesenchymal stem cells (MSCs)

  Published in Aging on February 23, 2023

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• Research PaperVolume 15, Issue 8pp 2891-2905

  Senescence-related genes define prognosis, immune contexture, and pharmacological response in gastric cancer

  Relevance score: 0.00

  Xiaogang Shen, Meng Wang, Wenxi Chen, Yu Xu, Qiaoxia Zhou, Tengfei Zhu, Guoqiang Wang, Shangli Cai, Yusheng Han, Chunwei Xu, Wenxian Wang, Lei Meng, Hao Sun

  Keywords: gastric cancer, senescence, prognosis, tumor immune microenvironment

  Published in Aging on February 16, 2023

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• Research PaperVolume 14, Issue 19pp 7692-7717

  Natural variation in macrophage polarization and function impact pneumocyte senescence and susceptibility to fibrosis

  Relevance score: 0.00

  Eun Joo Chung, Seokjoo Kwon, Uma Shankavaram, Ayla O. White, Shaoli Das, Deborah E. Citrin

  Keywords: senescence, macrophage, alveolar epithelial cell Type II, strain

  Published in Aging on September 28, 2022

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