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• Research Paper

  Chronic stress promotes premature ovarian failure in mice by inhibiting ovarian granulosa cell autophagy through PI3K-AKTmTOR pathway

  Relevance score: 0.00

  Zhibin Zhao, Xuefei Yuan, Baohua Zhao, Kai He

  Keywords: PI3K-AKT-mTOR pathway, premature ovarian failure (POF), ovarian granulosa cells (OGCs), chronic stress

  Published in Aging on October 8, 2024

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• Research PaperVolume 15, Issue 9pp 3381-3393

  PI3K-Akt signaling pathway based on network pharmacology for the anti-Alzheimer’s disease effect of licorice stem flavonoids

  Relevance score: 0.00

  Hongyan Pei, Lei He, Meiling Shi, Xiangjuan Guo, Weijia Chen, Jianming Li, Zhongmei He, Rui Du

  Keywords: network pharmacology, Alzheimer’s disease, licorice stem flavonoids, PI3K-Akt signalling pathway

  Published in Aging on February 22, 2023

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• Research PaperVolume 14, Issue 5pp 2418-2431

  miRNA-29a inhibits atherosclerotic plaque formation by mediating macrophage autophagy via PI3K/AKT/mTOR pathway

  Relevance score: 0.00

  Weihua Shao, Suxing Wang, Xiaoxi Wang, Lixia Yao, Xiaoye Yuan, Dai Huang, Bonan Lv, Yuquan Ye, Hongyuan Xue

  Keywords: PI3K/AKT/mTOR, miR-29a, macrophage, plaque, atherosclerotic, atherosclerosis

  Published in Aging on March 14, 2022

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• Research PaperVolume 13, Issue 6pp 7872-7882

  PI3K/AKT/MTOR and ERK1/2-MAPK signaling pathways are involved in autophagy stimulation induced by caloric restriction or caloric restriction mimetics in cortical neurons

  Relevance score: 0.00

  Marisa Ferreira-Marques, André Carvalho, Cláudia Cavadas, Célia A. Aveleira

  Keywords: aging, autophagy, cortical neurons, caloric restriction mimetics

  Published in Aging on March 14, 2021

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• Research PaperVolume 12, Issue 10pp 9489-9499

  PI3K-Akt-mTOR inhibition by GNE-477 inhibits renal cell carcinoma cell growth in vitro and in vivo

  Relevance score: 0.00

  Xueting Ye, Jian-Wei Ruan, Hang Huang, Wei-Ping Huang, Yan Zhang, Fangyi Zhang

  Keywords: renal cell carcinoma, PI3K-Akt-mTOR, GNE-477, molecularly-targeted therapies

  Published in Aging on May 18, 2020

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• Research PaperVolume 15, Issue 20pp 11162-11183

  Machine learning developed a PI3K/Akt pathway-related signature for predicting prognosis and drug sensitivity in ovarian cancer

  Relevance score: 0.00

  Xiaofang Han, Liu Yang, Hui Tian, Yuanyuan Ji

  Keywords: immunotherapy, prognostic signature, ovarian cancer, machine learning, PI3K/Akt pathway

  Published in Aging on October 17, 2023

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• Research PaperVolume 14, Issue 24pp 10081-10092

  SALL4 activates PI3K/AKT signaling pathway through targeting PTEN, thus facilitating migration, invasion and proliferation of hepatocellular carcinoma cells

  Relevance score: 0.00

  Zhipeng Tang, Pei Zhao, Wanxing Zhang, Qian Zhang, Ming Zhao, He Tan

  Keywords: SALL4, hepatocellular carcinoma cells, migration, invasion, proliferation

  Published in Aging on December 26, 2022

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• Research PaperVolume 12, Issue 14pp 14830-14848

  FGF2-induced PI3K/Akt signaling evokes greater proliferation and adipogenic differentiation of human adipose stem cells from breast than from abdomen or thigh

  Relevance score: 0.00

  Guan-Ming Lu, Yong-Xian Rong, Zhi-Jie Liang, Dong-Lin Hunag, Fang-Xiao Wu, Yan-Fei Ma, Zhi-Zhai Luo, Xin-Heng Liu, Steven Mo, Hong-Mian Li

  Keywords: adipose-derived stem cells, molecular signature, paracrine, adipogenic differentiation, depot-specific stem cell populations

  Published in Aging on July 24, 2020

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• Research PaperVolume 12, Issue 8pp 6852-6864

  Swimming exercise stimulates IGF1/ PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus

  Relevance score: 0.00

  Jing-Ying Lin, Wei-Wen Kuo, Rathinasamy Baskaran, Chia-Hua Kuo, Yun-An Chen, William Shao-Tsu Chen, Tsung-Jung Ho, Cecilia Hsuan Day, B. Mahalakshmi, Chih-Yang Huang

  Keywords: swimming exercise, induced-aging rats, hippocampus, inflammatory, apoptosis

  Published in Aging on April 22, 2020

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• Research PaperVolume 15, Issue 15pp 7831-7843

  Anhydroicaritin suppresses tumor progression via the PI3K/AKT signaling pathway in hepatocellular carcinoma

  Relevance score: 0.00

  Houhong Wang, Wenli Chen, Yayun Cui, Huihui Gong, Amao Tang

  Keywords: Bushen Huayu Decoction, Anhydroicaritin, hepatocellular carcinoma, molecular docking, experimental validation

  Published in Aging on August 8, 2023

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• Research PaperVolume 14, Issue 18pp 7505-7516

  ZCCHC12 promotes the progression of osteosarcoma via PI3K/AKT pathway

  Relevance score: 0.00

  Yong Cui, Yong-Yong Dong

  Keywords: OS, ZCCHC12, PI3K, AKT

  Published in Aging on September 19, 2022

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• Research PaperVolume 13, Issue 17pp 21090-21101

  Effect of the Notch1-mediated PI3K-Akt-mTOR pathway in human osteosarcoma

  Relevance score: 0.00

  Kexiang Zhang, Song Wu, Hongwei Wu, Li Liu, Jiahui Zhou

  Keywords: osteosarcoma, Notch1, autophagy, PI3K/Akt/mTOR

  Published in Aging on September 8, 2021

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• Research PaperVolume 13, Issue 11pp 15444-15458

  Alterations in the RTK/Ras/PI3K/AKT pathway serve as potential biomarkers for immunotherapy outcome of diffuse gliomas

  Relevance score: 0.00

  Song Han, Peng-Fei Wang, Hong-Qing Cai, Jing-Hai Wan, Shou-Wei Li, Ze-Huan Lin, Chun-Jiang Yu, Chang-Xiang Yan

  Keywords: gliomas, immunotherapy, small-molecule kinase inhibitors, bioinformatic analysis

  Published in Aging on June 8, 2021

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• Research PaperVolume 13, Issue 9pp 13225-13238

  TRIM14 regulates melanoma malignancy via PTEN/PI3K/AKT and STAT3 pathways

  Relevance score: 0.00

  Jiangyan Chen, Lin Huang, Jin Quan, Debing Xiang

  Keywords: TRIM14, melanoma, AKT, STAT3

  Published in Aging on May 11, 2021

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• Research PaperVolume 13, Issue 10pp 13626-13643

  E2F2 inhibition induces autophagy via the PI3K/Akt/mTOR pathway in gastric cancer

  Relevance score: 0.00

  Hui Li, Shufen Zhao, Liwei Shen, Peige Wang, Shihai Liu, Yingji Ma, Zhiwei Liang, Gongjun Wang, Jing Lv, Wensheng Qiu

  Keywords: gastric cancer, E2F2, autophagy, metastasis, PI3K/Akt/mTOR pathway

  Published in Aging on April 21, 2021

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• CorrectionVolume 12, Issue 16pp 16663-16664

  Correction for: Swimming exercise stimulates IGF1/PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus

  Relevance score: 0.00

  Jing-Ying Lin, Wei-Wen Kuo, Rathinasamy Baskaran, Chia-Hua Kuo, Yun-An Chen, William Shao-Tsu Chen, Tsung-Jung Ho, Cecilia Hsuan Day, B. Mahalakshmi, Chih-Yang Huang

  Keywords: correction

  Published in Aging on August 30, 2020

• Research PaperVolume 11, Issue 22pp 10697-10710

  MAP2K4 interacts with Vimentin to activate the PI3K/AKT pathway and promotes breast cancer pathogenesis

  Relevance score: 0.00

  Shu Liu, Juan Huang, Yewei Zhang, Yiyi Liu, Shi Zuo, Rong Li

  Keywords: MAP2K4, breast cancer, PI3K/AKT pathway, Vimentin

  Published in Aging on November 25, 2019

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• Research PaperVolume 10, Issue 10pp 2772-2782

  Autophagy of macrophages is regulated by PI3k/Akt/mTOR signalling in the development of diabetic encephalopathy

  Relevance score: 0.00

  Beiyun Wang, Yuan Zhong, Qinjie Li, Liang Cui, Gaozhong Huang

  Keywords: diabetes, diabetic encephalopathy (DE), inflammatory macrophages, autophagy, mTOR

  Published in Aging on October 22, 2018

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• Research Paper

  MiR-125b realizes anti-tumor action via PI3K/Akt/GSK3β pathway by targeting PIK3CD in hepatocellular carcinoma

  Relevance score: 0.00

  Honglei Che, Xiaodong Jia, Lingzhan Meng, Hu Li, Xiaofeng Zhang, Yunlong Zhuang, Xiaofeng Niu, Yu Zhang, Yinjie Gao, Zhenyu Zhu

  Keywords: hepatocellular carcinom, MiR-125b, PI3K/Akt/GSK3β, PIK3CD

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• Research PaperVolume 16, Issue 19pp 12806-12819

  FGA influences invasion and metastasis of hepatocellular carcinoma through the PI3K/AKT pathway

  Relevance score: 0.00

  Xi Han, Zefeng Liu, Mengying Cui, Jie Lin, Yongzhi Li, Hanjiao Qin, Jiyao Sheng, Xuewen Zhang

  Keywords: FGA, hepatocellular carcinoma, PI3K, AKT, metastasis

  Published in Aging on July 9, 2024

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