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• Research PaperVolume 13, Issue 3pp 4274-4290

  The roles of PARP-1 and XPD and their potential interplay in repairing bupivacaine-induced neuron oxidative DNA damage

  Relevance score: 0.00

  Wei Zhao, Zhongjie Liu, Jiaming Luo, Changqing Ma, Luying Lai, Zhengyuan Xia, Shiyuan Xu

  Keywords: DNA damage repair, oxidative stress, neurotoxicity, bupivacaine

  Published in Aging on January 20, 2021

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• Research PaperVolume 11, Issue 23pp 11268-11313

  The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage

  Relevance score: 0.00

  Jaana van Gastel, Hanne Leysen, Paula Santos-Otte, Jhana O. Hendrickx, Abdelkrim Azmi, Bronwen Martin, Stuart Maudsley

  Keywords: relaxin family peptide 3 receptor, relaxin 3, GPCR, DNA damage, aging

  Published in Aging on December 3, 2019

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• Research PaperVolume 10, Issue 4pp 549-560

  Unrepaired DNA damage in macrophages causes elevation of particulate matter- induced airway inflammatory response

  Relevance score: 0.00

  Man Luo, Zhengqiang Bao, Feng Xu, Xiaohui Wang, Fei Li, Wen Li, Zhihua Chen, Songmin Ying, Huahao Shen

  Keywords: DNA damage, DNA damage response, macrophages, particulate matter, airway inflammation

  Published in Aging on April 14, 2018

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• Research PaperVolume 8, Issue 1pp 147-155

  DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age

  Relevance score: 0.00

  Mariëtte E.C. Waaijer, Eleonora Croco, Rudi G.J. Westendorp, P. Eline Slagboom, John M. Sedivy, Antonello Lorenzini, Andrea B. Maier

  Keywords: human aging, 53BP1, telomere-associated foci, micronuclei, biological age

  Published in Aging on January 30, 2016

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• ReviewVolume 6, Issue 6pp 432-439

  Aging and DNA damage in humans: a meta-analysis study

  Relevance score: 0.00

  Jorge Pinto Soares, António Cortinhas, Teresa Bento, José Carlos Leitão, Andrew R. Collins, Isabel Gaivã, Maria Paula Mota

  Keywords: DNA damage, age, humans, meta-analysis, lifestyle

  Published in Aging on June 5, 2014

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• Research PaperVolume 6, Issue 6pp 496-510

  DNA damage signaling regulates age-dependent proliferative capacity of quiescent inner ear supporting cells

  Relevance score: 0.00

  Maarja Laos, Tommi Anttonen, Anna Kirjavainen, Taija af Hällström, Marikki Laiho, Ulla Pirvola

  Keywords: DNA damage, DNA repair, cell cycle re-entry, regeneration, supporting cell, hair cell, inner ear

  Published in Aging on May 21, 2014

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• Research PaperVolume 1, Issue 2pp 212-218

  Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells

  Relevance score: 0.00

  Asako J. Nakamura, Christophe E. Redon, William M. Bonner, Olga A. Sedelnikova

  Keywords: DNA damage, double-strand breaks, γ-H2AX, metaphase, telomeres, tumors

  Published in Aging on February 4, 2009

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• Research PerspectiveVolume 13, Issue 3pp 3167-3175

  DNA- and telomere-damage does not limit lifespan: evidence from rapamycin

  Relevance score: 0.00

  Mikhail V. Blagosklonny

  Keywords: quasi-programmed aging, hyperfunction theory, antagonistic pleiotropy, natural selection, mTOR

  Published in Aging on February 12, 2021

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• EditorialVolume 11, Issue 19pp 8039-8040

  Damaged DNA marching out of aging nucleus

  Relevance score: 0.00

  Nir Hacohen, Yuk Yuen Lan

  Keywords: DNASE2, DNA sensing, inflammation, cellular senescence, STING

  Published in Aging on October 2, 2019

• ReviewVolume 9, Issue 7pp 1647-1659

  Corrupting the DNA damage response: a critical role for Rad52 in tumor cell survival

  Relevance score: 0.00

  Rachel Lieberman, Ming You

  Keywords: Rad52, DNA damage response, squamous cell carcinoma of the lung, pre‐clinical model, tumor growth

  Published in Aging on July 15, 2017

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• Research PaperVolume 8, Issue 1pp 158-176

  To senesce or not to senesce: how primary human fibroblasts decide their cell fate after DNA damage

  Relevance score: 0.00

  Gabriel Kollarovic, Maja Studencka, Lyubomira Ivanova, Claudia Lauenstein, Kristina Heinze, Anastasiya Lapytsko, Soheil Rastgou Talemi, Ana Sofia Figueiredo, Jörg Schaber

  Keywords: G1-S transition, bistable hysteresis switch, dynamic model, Cdk2/p21 ratio, cumulative DNA damage

  Published in Aging on January 30, 2016

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• ReviewVolume 2, Issue 12pp 900-907

  The DNA damage response: Balancing the scale between cancer and ageing

  Relevance score: 0.00

  Elena G. Seviour, Shiaw-Yih Lin

  Keywords: aging, cancer, DNA damage, p53, senescence, ATM

  Published in Aging on December 16, 2010

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• Research PaperVolume 11, Issue 21pp 9829-9845

  Slower rates of accumulation of DNA damage in leukocytes correlate with longer lifespans across several species of birds and mammals

  Relevance score: 0.00

  Kurt Whittemore, Eva Martínez-Nevado, Maria A. Blasco

  Keywords: species, lifespan, DNA damage, short telomeres

  Published in Aging on November 15, 2019

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• Research PaperVolume 3, Issue 10pp 1028-1038

  Genome protective effect of metformin as revealed by reduced level of constitutive DNA damage signaling

  Relevance score: 0.00

  H. Dorota Halicka, Hong Zhao, Jiangwei Li, Frank Traganos, Sufang Zhang, Marietta Lee, Zbigniew Darzynkiewicz

  Keywords: DNA replication stress, Reactive oxidant species (ROS), H2AX phosphorylation, ATM activation, cell cycle

  Published in Aging on October 28, 2011

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• Research PaperVolume 15, Issue 17pp 8576-8593

  Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes

  Relevance score: 0.00

  Mélina Georget, Anaïs Defois, Romain Guiho, Nina Bon, Sophie Allain, Cécile Boyer, Boris Halgand, Denis Waast, Gaël Grimandi, Alban Fouasson-Chailloux, Jérôme Guicheux, Claire Vinatier

  Keywords: senescence, osteoarthritis, etoposide, IL-1β, chondrocytes

  Published in Aging on September 1, 2023

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• Research PaperVolume 14, Issue 20pp 8179-8204

  Crosstalk between age accumulated DNA-damage and the SIRT1-AKT-GSK3ß axis in urine derived renal progenitor cells

  Relevance score: 0.00

  Lars Erichsen, James Adjaye

  Keywords: renal differentiation, aging, SIRT1, DNA-damage

  Published in Aging on September 24, 2022

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• Research PaperVolume 13, Issue 21pp 24136-24154

  Mutations in DNA damage response pathways as a potential biomarker for immune checkpoint blockade efficacy: evidence from a seven-cancer immunotherapy cohort

  Relevance score: 0.00

  Wenjing Zhang, Liwen Zhang, Hao Jiang, Yuting Li, Suzhen Wang, Qinghua Wang

  Keywords: immunotherapy, DDR mutations, predictive biomarker, microenvironment, clinical practice

  Published in Aging on November 8, 2021

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• Research PaperVolume 13, Issue 11pp 15193-15213

  TRDMT1 participates in the DNA damage repair of granulosa cells in premature ovarian failure

  Relevance score: 0.00

  Chunli Sha, Lu Chen, Li Lin, Taoqiong Li, Hong Wei, Meiling Yang, Wujiang Gao, Dan Zhao, Qi Chen, Yueqin Liu, Xiaofang Chen, Wenlin Xu, Yuefeng Li, Xiaolan Zhu

  Keywords: premature ovarian failure, ROS, TRDMT1, DNA damage, granulosa cells

  Published in Aging on June 8, 2021

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• Priority Research PaperVolume 12, Issue 12pp 11165-11184

  SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair

  Relevance score: 0.00

  Sarallah Rezazadeh, David Yang, Seyed Ali Biashad, Denis Firsanov, Masaki Takasugi, Michael Gilbert, Gregory Tombline, Natarajan V. Bhanu, Benjamin A. Garcia, Andrei Seluanov, Vera Gorbunova

  Keywords: SIRT6, DNA repair, transcription, genome stability, longevity

  Published in Aging on June 25, 2020

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• Research PaperVolume 10, Issue 3pp 322-338

  Deficiency in DNA damage response of enterocytes accelerates intestinal stem cell aging in Drosophila

  Relevance score: 0.00

  Joung-Sun Park, Ho-Jun Jeon, Jung-Hoon Pyo, Young-Shin Kim, Mi-Ae Yoo

  Keywords: Drosophila, enterocyte, niche, DNA damage response, intestinal stem cell aging

  Published in Aging on March 7, 2018

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