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• Research PaperVolume 10, Issue 3pp 492-514

  Strong impact of natural-selection–free heterogeneity in genetics of age-related phenotypes

  Relevance score: 0.00

  Alexander M. Kulminski, Jian Huang, Yury Loika, Konstantin G. Arbeev, Olivia Bagley, Arseniy Yashkin, Matt Duan, Irina Culminskaya

  Keywords: genome-wide association studies, pleiotropy, age-related phenotypes, antagonistic genetic heterogeneity, aging, health span, life span

  Published in Aging on March 29, 2018

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• Research PaperVolume 6, Issue 1pp 58-69

  Indy gene variation in natural populations confers fitness advantage and life span extension through transposon insertion

  Relevance score: 0.00

  Chen-Tseh Zhu, Chengyi Chang, Robert A. Reenan, Stephen L. Helfand

  Keywords: Drosophila melanogaster, Indy, Hoppel, natural transposon, fitness, fertility, life span, longevity, aging, selective sweep, metabolism, genetic variants, gene regulatory networks

  Published in Aging on January 31, 2014

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• ReviewVolume 1, Issue 5pp 444-450

  Adaptation, aging, and genomic information

  Relevance score: 0.00

  Michael R. Rose

  Keywords: Aging, adaptation, forces of natural selection, Hamiltonian research; experimental evolution

  Published in Aging on May 21, 2009

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• Research PerspectiveVolume 13, Issue 3pp 3167-3175

  DNA- and telomere-damage does not limit lifespan: evidence from rapamycin

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  Mikhail V. Blagosklonny

  Keywords: quasi-programmed aging, hyperfunction theory, antagonistic pleiotropy, natural selection, mTOR

  Published in Aging on February 12, 2021

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• Theory ArticleVolume 13, Issue 12pp 15699-15749

  Shifting epigenetic contexts influence regulatory variation and disease risk

  Relevance score: 0.00

  Daniel Richard, Terence D. Capellini

  Keywords: development, aging, evolution, GWAS, disease

  Published in Aging on June 16, 2021

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• Research PaperVolume 8, Issue 10pp 2568-2589

  Empirical verification of evolutionary theories of aging

  Relevance score: 0.00

  Pavlo Kyryakov, Alejandra Gomez-Perez, Anastasia Glebov, Nimara Asbah, Luigi Bruno, Carolynne Meunier, Tatiana Iouk, Vladimir I. Titorenko

  Keywords: yeast, aging, longevity, evolution, ecosystems

  Published in Aging on October 25, 2016

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• HypothesisVolume 5, Issue 4pp 227-233

  Big mice die young but large animals live longer

  Relevance score: 0.00

  Mikhail V. Blagosklonny

  Keywords: MTOR, rapamycin, aging, geroconversion, gerosuppression

  Published in Aging on April 20, 2013

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• Research PaperVolume 8, Issue 11pp 3045-3064

  On the heterogeneity of human populations as reflected by mortality dynamics

  Relevance score: 0.00

  Demetris Avraam, Séverine Arnold, Olga Vasieva, Bakhtier Vasiev

  Keywords: mortality dynamics, mathematical modeling, model fitting, demography, population genetics

  Published in Aging on November 22, 2016

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• Research PaperVolume 3, Issue 2pp 125-147

  Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. elegans mutants

  Relevance score: 0.00

  Robert J. Shmookler Reis, Lulu Xu, Hoonyong Lee, Minho Chae, John J. Thaden, Puneet Bharill, Cagdas Tazearslan, Eric Siegel, Ramani Alla, Piotr Zimniak, Srinivas Ayyadevara

  Keywords: Aging, longevity, lipid (Fatty Acid), lipoperoxidation, nematode, RNAi

  Published in Aging on February 25, 2011

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• Research PaperVolume 4, Issue 9pp 606-619

  Aging induced decline in T-lymphopoiesis is primarily dependent on status of progenitor niches in the bone marrow and thymus

  Relevance score: 0.00

  Liguang Sun, Robert Brown, Shande Chen, Qichuan Zhuge, Dong-Ming Su

  Keywords: Hematopoiesis, bone marrow, T-lineage cells, niche cells, microenvironment, thymic stromal cells, aging, competitive repopulation

  Published in Aging on October 8, 2012

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• Research PaperVolume 17, Issue 3pp 798-821

  Decreased surface receptors, function, and suboptimal osteoclasts-induced cell expansion in natural killer (NK) cells of elderly subjects

  Relevance score: 0.00

  Kawaljit Kaur, Anahid Jewett

  Keywords: NK cells, osteoclasts, supercharged NK cells, expansion, IFN-γ

  Published in Aging on March 26, 2025

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• Research PaperVolume 15, Issue 15pp 7362-7380

  Natural aging and ovariectomy induces parallel phosphoproteomic alterations in skeletal muscle of female mice

  Relevance score: 0.00

  Mina P. Peyton, Tzu-Yi Yang, LeeAnn Higgins, Todd W. Markowski, Kevin Murray, Cha Vue, Laurie L. Parker, Dawn A. Lowe

  Keywords: estrogen deficiency, CAST, MAPK, PKA, calcineurin

  Published in Aging on August 14, 2023

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• Research PaperVolume 14, Issue 19pp 7692-7717

  Natural variation in macrophage polarization and function impact pneumocyte senescence and susceptibility to fibrosis

  Relevance score: 0.00

  Eun Joo Chung, Seokjoo Kwon, Uma Shankavaram, Ayla O. White, Shaoli Das, Deborah E. Citrin

  Keywords: senescence, macrophage, alveolar epithelial cell Type II, strain

  Published in Aging on September 28, 2022

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• Research PaperVolume 13, Issue 9pp 12565-12586

  Investigation and verification of the clinical significance and perspective of natural killer group 2 member D ligands in colon adenocarcinoma

  Relevance score: 0.00

  Guo-Tian Ruan, Shuai Wang, Li-Chen Zhu, Xi-Wen Liao, Xiang-Kun Wang, Cun Liao, Ling Yan, Hai-Lun Xie, Yi-Zhen Gong, Jia-Liang Gan, Feng Gao

  Keywords: natural killer group 2 member D ligands, verification, colon adenocarcinoma, diagnosis, prognosis

  Published in Aging on April 27, 2021

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• Research PaperVolume 12, Issue 23pp 23822-23835

  Calreticulin increases growth and progression of natural killer/T-cell lymphoma

  Relevance score: 0.00

  Yan Zheng, Chuntuan Li, Pengliang Xin, Qunyi Peng, Weiyu Zhang, Shengquan Liu, Xiongpeng Zhu

  Keywords: natural killer/T-cell lymphoma, calreticulin, growth, migration, epithelial-mesenchymal transition

  Published in Aging on November 18, 2020

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• Research PaperVolume 9, Issue 10pp 2069-2082

  Natural product celastrol suppressed macrophage M1 polarization against inflammation in diet-induced obese mice via regulating Nrf2/HO-1, MAP kinase and NF-κB pathways

  Relevance score: 0.00

  Dan Luo, Yumeng Guo, Yuanyuan Cheng, Jia Zhao, Yu Wang, Jianhui Rong

  Keywords: obesity, inflammation, adipose tissue, liver, macrophage polarization, celastrol

  Published in Aging on October 16, 2017

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• Research PaperVolume 17, Issue 11pp 2778-2808

  A natural language processing–driven map of the aging research landscape

  Relevance score: 0.00

  Jose Perez-Maletzki, Jorge Sanz-Ros

  Keywords: aging, literature mining, natural language processing, topic modelling, synthesis

  Published in Aging on November 25, 2025

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• Research PaperVolume 14, Issue 11pp 4874-4887

  Effective natural inhibitors targeting IGF-1R by computational study

  Relevance score: 0.00

  Xinyu Wang, Pengcheng Zhou, Liangxin Lin, Bo Wu, Zhaoyu Fu, Xing Huang, Dong Zhu

  Keywords: Ewing sarcoma, IGF-1R, drug therapy, natural compounds, virtual screening

  Published in Aging on June 9, 2022

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• Research PaperVolume 13, Issue 2pp 1898-1912

  Effective natural inhibitors targeting poly ADP-ribose polymerase by computational study

  Relevance score: 0.00

  Sheng Zhong, Bo Wu, Wenzhuo Yang, Junliang Ge, Xiangheng Zhang, Zhenghe Chen, Hao Duan, Zhenqiang He, Yibing Liu, Hongyu Wang, Yuting Jiang, Zhiyun Zhang, Xinhui Wang, Weihang Li, Naimeng Liu, Xiaoyu Guo, Yonggao Mou

  Keywords: glioblastoma, PARP, natural products, drug treatment, virtual screening

  Published in Aging on January 23, 2021

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• Research PaperVolume 9, Issue 11pp 2245-2268

  Towards natural mimetics of metformin and rapamycin

  Relevance score: 0.00

  Alexander Aliper, Leslie Jellen, Franco Cortese, Artem Artemov, Darla Karpinsky-Semper, Alexey Moskalev, Andrew G. Swick, Alex Zhavoronkov

  Keywords: geroprotector, metformin, rapamycin, deep learning, natural, nutraceutical, compound screening

  Published in Aging on November 15, 2017

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