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• Research PaperVolume 8, Issue 8pp 1718-1734

  Biological and biophysics aspects of metformin-induced effects: cortex mitochondrial dysfunction and promotion of toxic amyloid pre-fibrillar aggregates

  Relevance score: 0.00

  Pasquale Picone, Silvia Vilasi, Fabio Librizzi, Marco Contardi, Domenico Nuzzo, Luca Caruana, Sara Baldassano, Antonella Amato, Flavia Mulè, Pier Luigi San Biagio, Daniela Giacomazza, Marta Di Carlo

  Keywords: Alzheimer’s disease, metformin, mitochondrial dysfunction, cell degeneration, mitochondrial pores, β-amyloid aggregation

  Published in Aging on July 28, 2016

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• Research PaperVolume 17, Issue 9pp 2369-2391

  Runx1 overexpression induces early onset of intervertebral disc degeneration

  Relevance score: 0.00

  Takanori Fukunaga, Martha Elena Diaz-Hernandez, John G. Heller, Changli Zhang, Hicham Drissi

  Keywords: cell senescence, aging, Runx1, nucleus pulposus, intervertebral disc degeneration

  Published in Aging on September 8, 2025

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• Research PaperVolume 11, Issue 22pp 10252-10265

  Metformin decreases LPS-induced inflammatory response in rabbit annulus fibrosus stem/progenitor cells by blocking HMGB1 release

  Relevance score: 0.00

  Yingchao Han, Feng Yuan, Chao Deng, Fan He, Yan Zhang, Hongxing Shen, Zhi Chen, Lie Qian

  Keywords: intervertebral disc degeneration, annulus fibrosis stem cells, cell senescence, HMGB1, metformin

  Published in Aging on November 26, 2019

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• Research PaperVolume 15, Issue 24pp 14764-14790

  Conjoint research of WGCNA, single-cell transcriptome and structural biology reveals the potential targets of IDD development and treatment and JAK3 involvement

  Relevance score: 0.00

  Yingjing Zhao, Yuxue Mu, Yujia Zou, Zhijian He, Tianxing Lu, Xinhui Wang, Weihang Li, Bo Gao

  Keywords: intervertebral disc degeneration, weighted gene co-expression network analysis, Janus kinase family, high-throughput virtual screening, single-cell transcriptome

  Published in Aging on December 12, 2023

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• Research PaperVolume 14, Issue 10pp 4572-4585

  Lactotransferrin promotes intervertebral disc degeneration by regulating Fas and inhibiting human nucleus pulposus cell apoptosis

  Relevance score: 0.00

  Xiao-Bo Zhang, Si-Qi Xu, Yi-Geng Hui, Hai-Yu Zhou, Yi-Cun Hu, Rui-Hao Zhang, Xi-Dan Gao, Chang-Ming Zheng

  Keywords: lactotransferrin, intervertebral disc degeneration, bioinformatics, nucleus pulposus cell, mechanism

  Published in Aging on May 25, 2022

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• Research PaperVolume 16, Issue 9pp 8044-8069

  Bioinformatics analysis for constructing a cellular senescence-related age-related macular degeneration diagnostic model and identifying relevant disease subtypes to guide treatment

  Relevance score: 0.00

  Shan Luo, Qiang Hu, Bo Jiang, Zhongyu Zhang, Dawei Sun

  Keywords: age-related macular degeneration, cellular senescence, programmed cell death, inflammatory response, molecular subtypes

  Published in Aging on May 10, 2024

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• Research PaperVolume 2, Issue 1pp 28-42

  Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: Relevance to age-related macular degeneration

  Relevance score: 0.00

  Shozo Sonoda, Parameswaran G. Sreekumar, Satoru Kase, Christine Spee, Stephen J Ryan, Ram Kannan, David R Hinton

  Keywords: retinal pigment epithelial cell, cell polarity, VEGF-A, PEDF, BMP-4, age-related macular degeneration

  Published in Aging on December 27, 2009

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• Research PaperVolume 12, Issue 21pp 21971-21991

  CircGLCE alleviates intervertebral disc degeneration by regulating apoptosis and matrix degradation through the targeting of miR-587/STAP1

  Relevance score: 0.00

  Zhonghui Chen, Weibing Zhang, Ming Deng, Yaming Li, Yan Zhou

  Keywords: CircGLCE, intervertebral disc degeneration, apoptosis, nucleus pulposus cell, miR-587

  Published in Aging on November 6, 2020

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• Research PerspectiveVolume 1, Issue 8pp 740-745

  What determines the switch between atrophic and neovascular forms ofage related macular degeneration? - the role of BMP4 induced senescence

  Relevance score: 0.00

  DanHong Zhu, Xuemei Deng, Jing Xu, David R Hinton

  Keywords: BMP4, age related macular degeneration, senescence, retinal pigment epithelial cell, oxidative stress

  Published in Aging on August 12, 2009

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• Priority Research PaperVolume 12, Issue 20pp 19834-19851

  Knockdown of Foxg1 in Sox9+ supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse utricle

  Relevance score: 0.00

  Yuan Zhang, Shasha Zhang, Zhonghong Zhang, Ying Dong, Xiangyu Ma, Ruiying Qiang, Yin Chen, Xia Gao, Chunjie Zhao, Fangyi Chen, Shuangba He, Renjie Chai

  Keywords: Foxg1, Sox9, supporting cells, hair cell regeneration, trans-differentiation

  Published in Aging on October 24, 2020

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• ReviewVolume 11, Issue 21pp 9947-9959

  Aging and stress induced β cell senescence and its implication in diabetes development

  Relevance score: 0.00

  Na Li, Furong Liu, Ping Yang, Fei Xiong, Qilin Yu, Jinxiu Li, Zhiguang Zhou, Shu Zhang, Cong-Yi Wang

  Keywords: senescence, β cell, β cell regeneration, insulin secretion, diabetes

  Published in Aging on November 13, 2019

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• Research PaperVolume 11, Issue 17pp 7070-7082

  Chondrocyte sheet in vivo cartilage regeneration technique using miR-193b-3p to target MMP16

  Relevance score: 0.00

  Xia Chen, Ruhong Zhang, Qun Zhang, Zhicheng Xu, Feng Xu, Datao Li, Yiyuan Li

  Keywords: cartilage regeneration, cell sheet, extracellular matrix (ECM), tissue engineering, miR-193b-3p

  Published in Aging on September 6, 2019

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• Research PaperVolume 4, Issue 12pp 966-977

  Complete cardiac regeneration in a mouse model of myocardial infarction

  Relevance score: 0.00

  Bernhard Johannes Haubner, Martyna Adamowicz-Brice, Sanjay Khadayate, Viktoria Tiefenthaler, Bernhard Metzler, Tim Aitman, Josef M. Penninger

  Keywords: Heart regeneration, cell cycle, heart disease

  Published in Aging on December 31, 2012

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• Research PaperVolume 13, Issue 10pp 13421-13429

  Systemic NF-κB-mediated inflammation promotes an aging phenotype in skeletal stem/progenitor cells

  Relevance score: 0.00

  Anne Marie Josephson, Kevin Leclerc, Lindsey H. Remark, Emma Muiños Lopeź, Philipp Leucht

  Keywords: regeneration, skeletal stem cell, aging, inflammation, nuclear factor kappa B

  Published in Aging on May 25, 2021

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• Research PerspectiveVolume 3, Issue 5pp 555-563

  Embryonic anti-aging niche

  Relevance score: 0.00

  Irina M. Conboy, Hanadie Yousef, Michael J. Conboy

  Keywords: stem cell aging, regeneration, niche, senescent, cell cycle, Notch, TGF-β, MAPK, muscle, hESC

  Published in Aging on May 31, 2011

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• EditorialVolume 11, Issue 18pp 7331-7333

  Adipogenic progenitors keep muscle stem cells young

  Relevance score: 0.00

  Sara Ancel, Omid Mashinchian, Jerome N. Feige

  Keywords: muscle stem cell, regeneration, aging, fibro/adipogenic progenitor, niche

  Published in Aging on September 19, 2019

• Research PaperVolume 17, Issue 6pp 1571-1580

  Enhancing oocyte activation in women with ovarian failure: clinical outcomes of the Stem Cell Regenera study using G-CSF mobilization of peripheral blood stem cells and intraovarian injection of stem cell factor-enriched platelet rich plasma in real-world-practice

  Relevance score: 0.00

  Amparo Santamaria, Ana Ballester, Manuel Muñoz

  Keywords: Stem Cell Regenera, oocyte activation, ovarian regeneration, G-CSF, SCFE-PRP, ovarian failure

  Published in Aging on June 27, 2025

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• EditorialVolume 15, Issue 7pp 2364-2366

  Senescent cells enhance ischemic aging in the female heart

  Relevance score: 0.00

  Daniele Torella, Nadia Salerno, Eleonora Cianflone

  Keywords: cell senescence, aging, cardiac stem cells, cardiac regeneration, female sex

  Published in Aging on March 23, 2023

• EditorialVolume 12, Issue 6pp 4685-4687

  Prometheus revisited: liver homeostasis and repair

  Relevance score: 0.00

  Tianliang Sun, Stefano Annunziato, Jan S. Tchorz

  Keywords: liver homeostasis, liver stem cell, AXIN2, LGR5, SOX9, liver regeneration

  Published in Aging on March 23, 2020

• Research PaperVolume 8, Issue 11pp 2871-2896

  Age-associated NF-κB signaling in myofibers alters the satellite cell niche and re-strains muscle stem cell function

  Relevance score: 0.00

  Juhyun Oh, Indranil Sinha, Kah Yong Tan, Bernard Rosner, Jonathan M. Dreyfuss, Ornela Gjata, Peter Tran, Steven E. Shoelson, Amy J. Wagers

  Keywords: satellite cell, skeletal muscle, aging, regeneration

  Published in Aging on November 14, 2016

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