Search

Search Results

51 results found. Results per page: [ 20 ] [ 40 ] [ 60 ] [ 80 ] [ 100 ] [ 200 ] [ 300 ]

Sort by: [ Publication Date ] [ Score ]

Direction: [ Desc ] [ Asc ]

Year of publication: [ 2026 ] [ 2025 ] [ 2024 ] [ 2023 ] [ 2022 ] [ 2021 ] [ 2020 ] [ 2019 ] [ 2018 ] [ 2017 ] [ 2016 ] [ 2015 ] [ 2014 ] [ 2013 ] [ 2012 ] [ 2011 ] [ 2010 ] [ 2009 ] [ Any ]

Page: 123 of 3

• Research PerspectiveVolume 12, Issue 8pp 6511-6517

  COVID-19 and chronological aging: senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection?

  Relevance score: 0.00

  Camillo Sargiacomo, Federica Sotgia, Michael P. Lisanti

  Keywords: COVID-19, corona virus, aging, senescence, senolytic drug therapy, prevention, viral replication, drug repurposing, antibiotic, Azithromycin, Hydroxy-chloroquine, Rapamycin, Doxycycline, Quercetin

  Published in Aging on March 30, 2020

  Show abstract
• Research PaperVolume 12, Issue 13pp 12750-12770

  Navitoclax (ABT263) reduces inflammation and promotes chondrogenic phenotype by clearing senescent osteoarthritic chondrocytes in osteoarthritis

  Relevance score: 0.00

  Hao Yang, Cheng Chen, Hao Chen, Xiaojun Duan, Juan Li, Yi Zhou, Weinan Zeng, Liu Yang

  Keywords: osteoarthritis, inflammation, cellular senescence, senolytic, chondrocytes

  Published in Aging on July 1, 2020

  Show abstract
• Research PaperVolume 12, Issue 3pp 2711-2722

  Dasatinib plus quercetin prevents uterine age-related dysfunction and fibrosis in mice

  Relevance score: 0.00

  Marcelo B. Cavalcante, Tatiana D. Saccon, Allancer D.C. Nunes, James L. Kirkland, Tamara Tchkonia, Augusto Schneider, Michal M. Masternak

  Keywords: aging, uterine fibrosis, senolytics, mRNA, miRNA

  Published in Aging on January 18, 2020

  Show abstract
• Research PaperVolume 11, Issue 8pp 2202-2216

  Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs)

  Relevance score: 0.00

  Marco Fiorillo, Fanni Tóth, Federica Sotgia, Michael P. Lisanti

  Keywords: Doxycycline, Azithromycin, Vitamin C, combination therapy, mitochondrial ATP depletion, glycolysis

  Published in Aging on April 19, 2019

  Show abstract
• Research PaperVolume 10, Issue 11pp 3294-3307

  Azithromycin and Roxithromycin define a new family of “senolytic” drugs that target senescent human fibroblasts

  Relevance score: 0.00

  Bela Ozsvari, John R. Nuttall, Federica Sotgia, Michael P. Lisanti

  Keywords: drug repurposing, aging, senescence, senolytic drugs, antibiotics, azithromycin, roxithromycin

  Published in Aging on November 14, 2018

  Show abstract
• Research PaperVolume 14, Issue 19pp 7650-7661

  Senolytic elimination of senescent macrophages restores muscle stem cell function in severely dystrophic muscle

  Relevance score: 0.00

  Lei Liu, Xianlin Yue, Zewei Sun, William S. Hambright, Qi Feng, Yan Cui, Johnny Huard, Paul D. Robbins, Zhihui Wang, Xiaodong Mu

  Keywords: muscular dystrophy, senolytics, cellular senescence, immunosenescence, stem cells

  Published in Aging on September 8, 2022

  Show abstract
• Research PaperVolume 12, Issue 9pp 8221-8240

  Identification of SYK inhibitor, R406 as a novel senolytic agent

  Relevance score: 0.00

  Hyun-Ji Cho, Eun Jae Yang, Joon Tae Park, Jae-Ryong Kim, Eok-Cheon Kim, Kyong-Jin Jung, Sang Chul Park, Young-Sam Lee

  Keywords: cellular senescence, senolytics, apoptosis, FAK, p38

  Published in Aging on May 7, 2020

  Show abstract
• Priority Research PaperVolume 13, Issue 10pp 13380-13392

  Cdkn1a transcript variant 2 is a marker of aging and cellular senescence

  Relevance score: 0.00

  José Alberto López-Domínguez, Sandra Rodríguez-López, Ulises Ahumada-Castro, Pierre-Yves Desprez, Maria Konovalenko, Remi-Martin Laberge, César Cárdenas, José Manuel Villalba, Judith Campisi

  Keywords: p21, p53, mouse dermal fibroblast, ionizing radiation, doxorubicin

  Published in Aging on May 25, 2021

  Show abstract
• Research PaperVolume 16, Issue 10pp 8599-8610

  Senolytic effects of exercise in human muscles require acute inflammation

  Relevance score: 0.00

  Wei-Horng Jean, Yin-Chou Lin, Pei-Yao Ang, Kazushige Goto, Chao-An Lin, Luthfia Dewi, Yu-Chieh Liao, Chih-Yang Huang, Chia-Hua Kuo

  Keywords: p16^INK4a, high-intensity intermittent exercise, cellular senescence, inflammation, NSAID

  Published in Aging on May 15, 2024

  Show abstract
• Research PaperVolume 14, Issue 15pp 6006-6027

  Senolytic drugs relieve pain by reducing peripheral nociceptive signaling without modifying joint tissue damage in spontaneous osteoarthritis

  Relevance score: 0.00

  Tae-Hwan Gil, Haiyan Zheng, Hyo Gyeong Lee, Ji-Won Shin, Sun Wook Hwang, Ki-Mo Jang, Ok Hee Jeon

  Keywords: senescence, spontaneous osteoarthritis, pain, senolytics, nociceptive pathways

  Published in Aging on August 10, 2022

  Show abstract
• Research PaperVolume 15, Issue 7pp 2373-2394

  Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic

  Relevance score: 0.00

  Fares Al-Mansour, Abdullah Alraddadi, Buwei He, Anes Saleh, Marta Poblocka, Wael Alzahrani, Shaun Cowley, Salvador Macip

  Keywords: senescence, senolytics, HDAC, PI3K, CUDC-907

  Published in Aging on March 28, 2023

  Show abstract
• Research PaperVolume 11, Issue 2pp 771-782

  The curcumin analog EF24 is a novel senolytic agent

  Relevance score: 0.00

  Wen Li, Yonghan He, Rongping Zhang, Guangrong Zheng, Daohong Zhou

  Keywords: cellular senescence, aging, curcumin, EF24, senolytic agent

  Published in Aging on January 28, 2019

  Show abstract
• Research PaperVolume 8, Issue 11pp 2915-2926

  Discovery of piperlongumine as a potential novel lead for the development of senolytic agents

  Relevance score: 0.00

  Yingying Wang, Jianhui Chang, Xingui Liu, Xuan Zhang, Suping Zhang, Xin Zhang, Daohong Zhou, Guangrong Zheng

  Keywords: piperlongumine, aging, senescent cells, senolytic agents, ABT-263, reactive oxygen species, synergistic effect

  Published in Aging on November 19, 2016

  Show abstract
• Research PaperVolume 15, Issue 23pp 13581-13592

  Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema

  Relevance score: 0.00

  Alberta Palazzo, Gabriela Makulyte, Delphine Goerhig, Jean-Jacques Médard, Vincent Gros, François Trottein, Serge Adnot, David Vindrieux, Jean-Michel Flaman, David Bernard

  Keywords: senolytic, cigarette smoke, lung disease, cellular senescence, calcium channel

  Published in Aging on December 12, 2023

  Show abstract
• Research PaperVolume 16, Issue 13pp 10694-10723

  Modulating in vitro lung fibroblast activation via senolysis of senescent human alveolar epithelial cells

  Relevance score: 0.00

  Joseph S. Spina, Tracy L. Carr, Lucy A. Phillips, Heather L. Knight, Nancy E. Crosbie, Sarah M. Lloyd, Manisha A. Jhala, Tony J. Lam, Jozsef Karman, Meghan E. Clements, Tovah A. Day, Justin D. Crane, William J. Housley

  Keywords: cellular senescence, fibrosis, senolytic, senomorphic, SASP, alveolar epithelial cell

  Published in Aging on June 29, 2024

  Show abstract
• Research PaperVolume 15, Issue 19pp 9984-10009

  BMAL1 modulates senescence programming via AP-1

  Relevance score: 0.00

  Sarah K. Jachim, Jian Zhong, Tamas Ordog, Jeong-Heon Lee, Aditya V. Bhagwate, Nagaswaroop Kengunte Nagaraj, Jennifer J. Westendorf, João F. Passos, Aleksey V. Matveyenko, Nathan K. LeBrasseur

  Keywords: AP-1, circadian clock, cellular senescence, senolytic, transcription regulation

  Published in Aging on October 10, 2023

  Show abstract
• Research PaperVolume 14, Issue 16pp 6381-6414

  Synergism of BCL-2 family inhibitors facilitates selective elimination of senescent cells

  Relevance score: 0.00

  David Rysanek, Pavla Vasicova, Jayaprakash Narayana Kolla, David Sedlak, Ladislav Andera, Jiri Bartek, Zdenek Hodny

  Keywords: homoharringtonine, cellular senescence, BCL-2, MCL-1, senolytics

  Published in Aging on August 8, 2022

  Show abstract
• Research PaperVolume 9, Issue 3pp 955-963

  New agents that target senescent cells: the flavone, fisetin, and the BCL-X_L inhibitors, A1331852 and A1155463

  Relevance score: 0.00

  Yi Zhu, Ewald J. Doornebal, Tamar Pirtskhalava, Nino Giorgadze, Mark Wentworth, Heike Fuhrmann-Stroissnigg, Laura J. Niedernhofer, Paul D. Robbins, Tamara Tchkonia, James L. Kirkland

  Keywords: senolytics, aging, adipose-derived stem cells, preadipocytes, apoptosis, flavonoids, BCL-X inhibitors _L

  Published in Aging on March 8, 2017

  Show abstract
• Research PaperVolume 17, Issue 1pp 97-115

  Senolytic agent ABT-263 mitigates low- and high-LET radiation-induced gastrointestinal cancer development in Apc^1638N/+ mice

  Relevance score: 0.00

  Kamendra Kumar, Bo-Hyun Moon, Santosh Kumar, Jerry Angdisen, Bhaskar V.S. Kallakury, Albert J. Fornace, Shubhankar Suman

  Keywords: senescence-associated secretory phenotype, senolytic agent, carcinogenesis, inflammation, β-catenin

  Published in Aging on January 8, 2025

  Show abstract
• Research PaperVolume 15, Issue 3pp 765-776

  Senolytic effect of high intensity interval exercise on human skeletal muscle

  Relevance score: 0.00

  Wei-Horng Jean, Yu-Wen Hsieh, Li-Fan Lai, Luthfia Dewi, Yu-Chieh Liao, Mengxin Ye, Szu-Hsien Yu, Chung-Lan Kao, Chih-Yang Huang, Chia-Hua Kuo

  Keywords: DNA repair, inflammation, p16^Ink4a, γ-H2AX, CD11b, HIIT, cycling

  Published in Aging on February 8, 2023

  Show abstract