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• Research PaperVolume 11, Issue 23pp 11591-11608

  Pharmacological inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and β-Amyloid plaques in an early-onset Alzheimer’s disease mouse model

  Relevance score: 0.00

  Christian Griñán-Ferré, Laura Marsal-García, Aina Bellver-Sanchis, Shukkoor Muhammed Kondengaden, Ravi Chakra Turga, Santiago Vázquez, Mercè Pallàs

  Keywords: G9a/GLP, epigenetics, neuroinflammation, synaptic plasticity, β-amyloid plaques

  Published in Aging on December 4, 2019

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• Research PaperVolume 8, Issue 4pp 664-684

  Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice

  Relevance score: 0.00

  Christian Griñán-Ferré, Sara Sarroca, Aleksandra Ivanova, Dolors Puigoriol-Illamola, Fernando Aguado, Antoni Camins, Coral Sanfeliu, Mercè Pallàs

  Keywords: Alzheimer disease, neurodegeneration, behavior, cognition, deacetylase, methyltransferase

  Published in Aging on March 21, 2016

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• Research PerspectiveVolume 3, Issue 8pp 803-812

  Phosphorylation of amyloid beta (Aβ) peptides – A trigger for formation of toxic aggregates in Alzheimer's disease

  Relevance score: 0.00

  Sathish Kumar, Jochen Walter

  Keywords: Alzheimer's disease, amyloid β-peptide, oligomers, phosphorylation, post translational modification, protein folding, conformation and aggregation

  Published in Aging on August 21, 2011

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• Research PaperVolume 8, Issue 12pp 3430-3449

  Early and progressive deficit of neuronal activity patterns in a model of local amyloid pathology in mouse prefrontal cortex

  Relevance score: 0.00

  Fani Koukouli, Marie Rooy, Uwe Maskos

  Keywords: Alzheimer’s Disease, AAV, human mutated APP, chronic two-photon imaging, neuronal synchronicity

  Published in Aging on December 20, 2016

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• Research PaperVolume 12, Issue 1pp 1011-1033

  Down syndrome and Alzheimer's disease: common molecular traits beyond the amyloid precursor protein

  Relevance score: 0.00

  Wileidy Gomez, Rodrigo Morales, Vinicius Maracaja-Coutinho, Valentina Parra, Melissa Nassif

  Keywords: Alzheimer's disease, Down syndrome, mitophagy, epigenetics, oxidative stress

  Published in Aging on January 9, 2020

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• ReviewVolume 13, Issue 17pp 21791-21806

  Involvement of cerebrovascular abnormalities in the pathogenesis and progression of Alzheimer’s disease: an adrenergic approach

  Relevance score: 0.00

  Song Li, Che Wang, Zhen Wang, Jun Tan

  Keywords: Alzheimer's disease, adrenergic receptors, β-amyloid, cerebrovascular, tau

  Published in Aging on September 3, 2021

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• Research PaperVolume 13, Issue 8pp 11150-11169

  The neuroprotection of deproteinized calf blood extractives injection against Alzheimer's disease via regulation of Nrf-2 signaling

  Relevance score: 0.00

  Yidi Qu, Wenqi Wang, Tianrui Chen, Yumin Yang, Yizhi Zhang, Di Wang

  Keywords: Alzheimer’s disease, deproteinized calf blood extractives injection, apoptosis, oxidative stress, Nrf-2 pathway

  Published in Aging on March 26, 2021

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• Research PaperVolume 12, Issue 21pp 22266-22290

  Cholesterol-rich naked mole-rat brain lipid membranes are susceptible to amyloid beta-induced damage in vitro

  Relevance score: 0.00

  Daniel Frankel, Matthew Davies, Bharat Bhushan, Yavuz Kulaberoglu, Paulina Urriola-Munoz, Justine Bertrand-Michel, Melissa R. Pergande, Andrew A. Smith, Swapan Preet, Thomas J. Park, Michele Vendruscolo, Kenneth S. Rankin, Stephanie M. Cologna, Janet R. Kumita, Nicolas Cenac, Ewan St John Smith

  Keywords: naked mole-rat, neurodegeneration, amyloid beta, brain, lipidomics

  Published in Aging on November 4, 2020

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• ReviewVolume 16, Issue 20pp 13145-13171

  Brain aging and Alzheimer’s disease, a perspective from non-human primates

  Relevance score: 0.00

  Ferrer Isidro

  Keywords: brain aging, macaques, baboon, chimpanzees, orang-utans

  Published in Aging on October 29, 2024

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• Research PaperVolume 12, Issue 20pp 20728-20742

  MicroRNA-338-5p alleviates neuronal apoptosis via directly targeting BCL2L11 in APP/PS1 mice

  Relevance score: 0.00

  Junhua Li, Danhua Li, Huatao Zhou, Guiyun Wu, Zhijie He, Wenhua Liao, Yujuan Li, Yaowei Zhi

  Keywords: Alzheimer's disease, MicroRNA-338-5p, neuronal apoptosis, BCL2L11

  Published in Aging on October 21, 2020

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• EditorialVolume 10, Issue 10pp 2544-2546

  Mutant ubiquitin reduces Aβ plaques

  Relevance score: 0.00

  Bert M. Verheijen, Fred W. van Leeuwen

  Keywords: mutant ubiquitin, ubiquitin-proteasome system, amyloid β, Aβ plaques, γ-secretase, proteostasis, Alzheimer’s disease

  Published in Aging on October 15, 2018

• Research PaperVolume 13, Issue 11pp 15285-15306

  Mesenchymal stem cells-derived extracellular vesicles ameliorate Alzheimer’s disease in rat models via the microRNA-29c-3p/BACE1 axis and the Wnt/β-catenin pathway

  Relevance score: 0.00

  Sha Sha, Xueli Shen, Yunpeng Cao, Le Qu

  Keywords: Alzheimer's disease, bone marrow mesenchymal stem cells, extracellular vesicles, microRNA-29c-3p, BACE1

  Published in Aging on June 4, 2021

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• Research PaperVolume 11, Issue 2pp 536-548

  Geniposide-mediated protection against amyloid deposition and behavioral impairment correlates with downregulation of mTOR signaling and enhanced autophagy in a mouse model of Alzheimer's disease

  Relevance score: 0.00

  Zhihua Zhang, Xiaojian Wang, Di Zhang, Yueze Liu, Lin Li

  Keywords: geniposide, APP/PS1 mice, mechanistic target of rapamycin, autophagy, Alzheimer’s disease

  Published in Aging on January 26, 2019

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• Research PaperVolume 11, Issue 19pp 8642-8663

  Decreased levels of circulating trimethylamine N-oxide alleviate cognitive and pathological deterioration in transgenic mice: a potential therapeutic approach for Alzheimer’s disease

  Relevance score: 0.00

  Qiang Gao, Yuan Wang, Xin Wang, Shuang Fu, Xin Zhang, Rui-Tao Wang, Xin Zhang

  Keywords: Alzheimer’s disease, APP/PS1 mice, trimethylamine-N-oxide, cognitive behavior, amyloid-β

  Published in Aging on October 14, 2019

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• Research PaperVolume 12, Issue 12pp 12142-12159

  Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice

  Relevance score: 0.00

  Fanlin Zhou, Xiaomin Xiong, Shijie Li, Jie Liang, Xiong Zhang, Mingyuan Tian, Xiaoju Li, Minna Gao, Li Tang, Yu Li

  Keywords: Alzheimer’s disease, dynein intermediate chain, autophagy, axonal transport

  Published in Aging on June 24, 2020

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• Research PaperVolume 15, Issue 19pp 10237-10252

  Ginkgolide attenuates memory impairment and neuroinflammation by suppressing the NLRP3/caspase-1 pathway in Alzheimer’s disease

  Relevance score: 0.00

  Guang-Zhi Liu, Tian-Tong Niu, Qian Yu, Bao-Lei Xu, Xiao-Qing Li, Bo-Yi Yuan, Guo-Bin Yuan, Ting-Ting Yang, Hui-Qin Li, Yi Sun

  Keywords: Alzheimer’s disease, amyloid beta, ginkgolide, microglia, NLRP3 inflammasome

  Published in Aging on October 3, 2023

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• Research PaperVolume 12, Issue 1pp 481-501

  A novel rhamnoside derivative PL402 up-regulates matrix metalloproteinase 3/9 to promote Aβ degradation and alleviates Alzheimer’s-like pathology

  Relevance score: 0.00

  Tingting Hu, Yue Zhou, Jing Lu, Peng Xia, Yue Chen, Xin Cao, Gang Pei

  Keywords: Alzheimer’s disease, Aβ degradation, matrix metalloproteinase 3/9, learning and memory deficits, natural products derivate

  Published in Aging on January 5, 2020

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• ReviewVolume 12, Issue 3pp 3095-3113

  Riluzole: a therapeutic strategy in Alzheimer’s disease by targeting the WNT/β-catenin pathway

  Relevance score: 0.00

  Alexandre Vallée, Jean-Noël Vallée, Rémy Guillevin, Yves Lecarpentier

  Keywords: Riluzole, Alzheimer's disease, WNT pathway, glutamate, oxidative stress

  Published in Aging on February 8, 2020

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• Research PaperVolume 11, Issue 16pp 6120-6133

  MicroRNA-181a protects against pericyte apoptosis via directly targeting FOXO1: implication for ameliorated cognitive deficits in APP/PS1 mice

  Relevance score: 0.00

  Qingbin Wu, Xiaochen Yuan, Jing Bai, Ruiqin Han, Zhigang Li, Honggang Zhang, Ruijuan Xiu

  Keywords: Alzheimer’s disease, MicroRNA-181a, pericyte, FOXO1, apoptosis

  Published in Aging on August 29, 2019

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• Research PaperVolume 13, Issue 14pp 18033-18050

  β-amyloid monomers drive up neuronal aerobic glycolysis in response to energy stressors

  Relevance score: 0.00

  Rosa Santangelo, Maria Laura Giuffrida, Cristina Satriano, Marianna Flora Tomasello, Stefania Zimbone, Agata Copani

  Keywords: Alzheimer’s disease, β-amyloid monomers, aerobic glycolysis, default mode network, lactate, oligomycin, kainate, AMPK

  Published in Aging on July 21, 2021

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